I usually use on famous people. For instance, if this person is well-known by certain nickname, fave hobby, a place he's associated with.
I've never used sequential unlocks but I'm keen to use it in future. E.g. In a history quiz, correctly identifying the year of the October Revolution or writing "Bolshevik" could unlock all of bolsheviks in that particular quiz.
Yes, on some of my (MKF)'s quizzes there are certain words I can use to have multiple answers awarded, mostly to help while testing/fixing. If anyone can find one then props to them