Diabetes drugs and T2DM management

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purplearwen
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Last updated: August 19, 2024
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First submittedAugust 19, 2024
Times taken20
Average score29.2%
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Answer
biguanide
metformin
sulphonylurea
gliclazide
thiazolidinedione
pioglitazone
GLP-1 agonist
exenatide
GLP-1 agonist
liraglutide
GLP-1 agonist
dulaglutide
DPP-4 inhibitor
sitagliptin
DPP-4 inhibitor
linagliptin
DPP-4 inhibitor
alogliptin
SGLT-2 inhibitor
empagliflozin
SGLT-2 inhibitor
dapagliflozin
SGLT-2 inhibitor
canagliflozin
Hint
Answer
1st line: QRISK<10%
1 metformin
at any point: QRISK>10%
add sglt-2 inhibitor
2nd line: normal BMI - meds cause weight gain
sulphonylurea, pioglitazone
2nd line: high BMI - cause weight loss
glp-1 agonist
2nd line: weight neutral - no effect on weight
dpp-4 inhibitor
3rd line
add 3rd drug or insulin
4th line: no insulin currently
swap for glp-1 agonist
4th line: insulin currently or 5th line
specialist
HbA1C target: no glucose altering meds
48
HbA1C target: glucose altering meds
53
Drugs causing renal impairment
metformin, sulphonylurea
Drugs offering cardio benefits
sglt-2 inhibitor, glp-1 agonist
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