Neuro - Neurodegenerative Disease - Statistics

General Stats
  • This quiz has been taken 38 times
    30 since last reset
  • The average score is 5 of 14
Answer Stats
Pathophysiology Condition % Correct
amyloid deposition (senile plaques) in brain and neurofibrillary tangles (tau proteins); cerebral cortex atrophy on CT Alzheimer's
78%
idiopathic dopamine depletion leading to failure to inhibit acetylcholine in the basal ganglia; cytoplasmia inclusions (lewy bodies) and loss of pigment cells in substantia nigra Parkinson's
70%
necrosis of upper and lower motor neurons causing progressive motor degeneration ALS
65%
autoimmune inflammatory demyelinating disease of CNS associated w/ axon degeneration of white matter in brain, optice nerve and spinal cord; white matter plaques (hyperdensities) on MRI w/ gadolinium, inc IgG (oligoclonal bands) in CSF Multiple Sclerosis
61%
localized brain degeneration of frontotemporal lobes, positive pick bodies Frontotemporal dementia (Pick's disease)
43%
diffuse deposition of lewy bodies (abnormal neuronal protein deposits) within brainΩ Lewy body dementia
43%
unilateral CN 7 (facial nerve) palsy associated w/ HSV reactivation due to inflammation or compression, LMN lesion Bell's palsy
35%
brain injury during perinatal or prenatal period Cerebral palsy
26%
autonomic dominant Cr 4 mutation that causes cerebral, putamen and caudate nucleus atrophy (and decreased glucose metabolism in those areas) Huntington's
26%
autoimmune peripheral nerve disorder associated w/ HLA-DR3; inefficient skeletal muscle neuromuscular transmission due to autoimmune ab against ach (nicotinic) postsynaptic receptor at neuromuscular junction leading to dec ach receptors; + Ach receptor ab, + MuSK (muscle specific tyrosine kinase) ab Myasthenia gravis
22%
chronic ischemia and multiple infarcts (ex. lacunar infarct) caused by hypertension Vascular dementia
22%
acquired inflammatory demyelinating polyradiculopathy of peripheral nerve; inc incidence w/ campylobacter jejuni or other antecedent respiratory/GI infections; immune mediated demyelination and axonal degeneration slowing nerve impulses; Guillain Barre
13%
cerebral inclusion (negri) bodies causing encephalitis Rabies
13%
multiple nodular or ring-enhancing lesions associated w/ vasogenic edema Toxoplasmosis
0%
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