| S # | Ep # | Episode Name | Actor | Diagnosis/Disease | % Correct |
|---|---|---|---|---|---|
| 4 | 8 | You Don't Want to Know | Steve Valentine (plays a magician) | Lupus (Autoimmune Hemolytic Anemia in Systemic Lupus Erythematosus) | 67%
|
| 7 | 5 | Unplanned Parenthood | Jennifer Grey (plays a mom of grown woman and a newborn) | Lung Cancer and Melanoma | 61%
|
| 2 | 4 | TB or Not TB | Ron Livingston (doctor specializing in TB) | Nesidioblastoma and Tuberculosis | 46%
|
| 5 | 8 | Birthmarks | Samantha Quan (woman looking for her parents in China) | Metal pins in brain (from attempted infanticide) | 43%
|
| 1 | 5 | Damned If You Do | Elizabeth Mitchell (played a nun) | Copper Allergy | 40%
|
| 1 | 1 | Everybody Lies (Pilot) | Robin Tunney (played a teacher) | Tapeworm (Neurocysticercosis) | 31%
|
| 2 | 18 | Sleeping Dogs Lie | Jayma Mays (worst insomnia ever) | Bubonic Plague | 29%
|
| 4 | 11 | Frozen | Mira Sorvino (she's at the south pole) | Fat Embolism | 29%
|
| 1 | 13 | Cursed | Daryl Sabara (boy joins a club in a vacant house) | Anthrax and Leprosy | 27%
|
| 2 | 17 | All In | Carter Page (young boy with same symptoms as an elderly woman) | Erdheim–Chester Disease | 26%
|
| 2 | 1 | Acceptance | LL Cool J (death row inmate) | Methanol Poisoning and Pheochromocytoma | 26%
|
| 1 | 7 | Fidelity | Myndy Crist (can't get out of bed) | African Sleeping Sickness | 23%
|
| 4 | 7 | Ugly | Khleo Thomas (getting major deformity removed while filming documentary) | Lyme Disease | 21%
|
| 2 | 9 | Deception | Cynthia Nixon (has a seizure at OTB when House was there, too) | Clostridium Perfringens and Munchausen Syndrome | 19%
|
| 7 | 7 | A Pox on Our House | Andrew Fiscella & Hayley Chase (father and stepdaughter back from a boat trip) | Rickettsialpox | 19%
|
| 4 | 9 | Games | Jeremy Renner (punk rocker and drug user) | Measles | 18%
|
| 3 | 7 | Son of Coma Guy | John Larroquette (the coma guy) | MERRF Syndrome (Myoclonic Epilepsy with Ragged Red Fibers) | 17%
|
| 6 | 10 | Wilson | Joshua Malina (plays Wilson's friends/patient) | Acute Lymphoblastic Leukemia | 15%
|
| 5 | 24 | Both Sides Now | Hugh Laurie (Yes, that guy) | Psychosis (Mental Illness) | 12%
|
| 7 | 9 | Larger Than Life | Matthew Lillard (rescues a stranger) | Chickenpox | 11%
|
| 8 | 5 | The Confession | Jamie Bamber (confesses to everything) | Kawasaki's Syndrome | 10%
|
| 8 | 8 | Transplant | Lungs in a Box (to be transplanted) | Eosinophilic Pneumonitis | 8%
|
| 6 | 4 | The Tyrant | James Earl Jones (plays a dictator) | Lung Infection (Blastomycosis) | 8%
|
| 6 | 15 | Private Lives | Laura Prepon (plays a blogger) | Whipple's Disease | 8%
|
| 3 | 3 | Informed Consent | Joel Grey (medical researcher who wants to die) | Congestive Heart Failure | 5%
|