Evil Doctors in Fiction

How many of these Evil Doctors can you name?

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Last updated: May 13, 2026

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First submitted	May 13, 2026
Times taken	3
Average score	56.5%
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Name	Debut	Hint
Dr Neo Cortex	Crash Bandicoot	Creator of the titular marsupial
Dr Nitrus Brio	Crash Bandicoot	His potion's are for two things; drinking and throwing
Dr N Gin	Crash Bandicoot 2; Cortex Strikes Back	The rocket in his head is pretty hard to ignore
Dr Nefarious Tropy	Crash Bandicoot Warped	Time Twisting genius aligned with Uka-Uka
Dr Nefario	Despicable Me	Gru's trusted inventor
Dr Olivia Pierce	DOOM (2016)	Unleashed the Lazarus Wave upon the UAC
Dr Betruger	Doom 3	Responsible for the Hell invasion in Doom 3
Doctor Doom	Fantastic 4	The armored ruler of Latveria
Dr Wallace Breen	Half-Life 2	Runs City 17 with some help from the Combine
Dr Claw	Inspector Gadget	Frequently seen petting his cat
Dr Drakken	Kim Possible	Where would he be without Shego?
Dr Wily	Mega Man	Loves his Skull Castles

Name	Debut	Hint
Dr Caballeron	My Little Pony: Friendship is Magic	Enemy of the not so fictional explorer, Daring Do
Dr Maruki	Persona 5 Royal	Good Intentioned Therapist
Dr Doofenshmertz	Phineas & Ferb	Has his very own Jingle!
Dr Facilier	Princess and the Frog	Turned a prince into a frog through his Voodoo
Dr Nefarious	Ratchet & Clank: Up Your Arsenal	Unhinged robot with a grudge against the Galactic Rangers
Dr Merlot	RWBY: Grimm Eclipse	Mutates the Monstrous Grimm
Dr Krankcase	Skylanders Trap Team	Evilikin Creator, and Goo Enthusiast
Dr Ivo "Eggman" Robotnik	Sonic the Hedgehog	Sometimes mockingly referred to as "Baldy Nosehair"
Dr Starline	Sonic the Hedgehog (IDW Comics)	The Brainwashing Platypus with his own Agenda
Doctor Octopus	Spider-Man	His four arms are borderline iconic
Dr Nuvo Vindi	Star Wars: The Clone Wars	Re-engineered the deadly Blue Shadow Virus

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