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Oh, No! You Died of Dysentery in 1850.

Whether you were following the Oregon Trail in 1850 or just making a living, infectious disease was a real threat.

Which infectious diseases killed the most US adults (ages 20-50) in 1850?
I filled in a couple that are unfamiliar today. You've heard of the rest!
These are in order according to how many lives they claimed.
Quiz by
Muncie
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Last updated: May 20, 2026
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First submittedMay 20, 2026
Times taken13
Average score71.4%
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Hint
Answer
C
caused by bacteria that contaminate food or water
cholera
F
a rise in body temperature
fever
T
spread by feces from an infected person
typhoid
D
gastroenteritis that results in bloody diarrhea.
dysentery
D
loose or watery bowel movements; can lead to dehydration
diarrhea
E
painful strep infection of the skin
erysipelas
S
this pox was eradicated in 1977
smallpox
Y
mosquitos cause this "colorful" rise in body temperature
yellow fever
C
we call it gastroenteritis or, informally, "stomach flu" today
cholera morbus
M
airborne disease preventable today by the MMR vaccine
measles
S
a strep infection causes this "colorful" rise in body temperature
scarlet fever
S
a form of typhus spread in close quarters, such as on a ship
ship fever
S
sexually transmitted disease
syphilis
C
characterized by a barking cough
croup
W
sometimes called the 100-day cough
whooping cough
I
infectious viral illness; modern vaccines may reduce its severity
influenza
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1 Comments
+1
Level 78
May 21, 2026
Great quiz! And even greater title.