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antiviral drugs - Statistics
General Stats
- This quiz has been taken 8 times
- The average score is 35 of 51
Answer Stats
| Hint | Answer | % Correct |
|---|---|---|
| what are the 3 types of viruses? | DNA viruses | 100%
|
| human immunodeficiency virus (HIV) 1 and 2, human T-lymphotropic viruses (HTLV) | 100%
| |
| inhibit replication or reverse transcription | 100%
| |
| neuraminidase inhibitors | 100%
| |
| what drug type is most commonly used to treat influenza? | neuraminidase inhibitors | 100%
|
| what is an example of each? | poxviruses (e.g. smallpox), herpesviruses (e.g. shingles), papillomaviruses (e.g. HPV) | 100%
|
| retroviruses | 100%
| |
| rhinoviruses (e.g. common cold), coronaviruses (e.g. Sars- CoV-2), influenza, rabies, measles | 100%
| |
| RNA viruses | 100%
| |
| uses protease to stop the virus from being release from the cell | 100%
| |
| airborne or droplet transmission | 83%
| |
| what is influenza? | an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae | 83%
|
| blocks the virus from uncoating within the cell | 83%
| |
| direct contact | 83%
| |
| entry inhibitors | 83%
| |
| fecal-oral transmission | 83%
| |
| genome replication | 83%
| |
| indirect contact | 83%
| |
| integrase inhibitors | 83%
| |
| what are their mechanisms of action? | it is an antiretroviral integrase inhibitor, and works by blocking the integrase enzyme needed to allow the viral DNA to integrate into the host genome, meaning the retrovirus cannot replicate | 83%
|
| protease inhibitors | 83%
| |
| what are the targets for antiviral drugs? | proteins that can be inhibited, particularly proteins that are conserved across species (and are dissimilar to human proteins) | 83%
|
| uncoating | 83%
| |
| uncoating inhibitors | 83%
| |
| what are the forms of viral transmission? | vector transmission | 83%
|
| vertical transmission | 83%
| |
| what are the main types of antiviral drugs? | attachment inhibitors | 67%
|
| blocks retroviruses from being able to perform reverse transcription | 67%
| |
| blocks the virion particles from being release from the cell | 67%
| |
| genome is comprised of RNA, but the virus converts this back into DNA and inserts a DNA copy of its genome into the host genome | 67%
| |
| is a nucleotide reverse transcriptase inhibitor whose active metabolite blocks the reverse transcription of HIV RNA into DNA | 67%
| |
| it is a nucleoside reverse transcriptase inhibitor whose active metabolite blocks the reverse transcription of HIV RNA into DNA | 67%
| |
| release of virions | 67%
| |
| how does it treat influenza? | their active metabolites competitively inhibit influenza virus neuraminidase enzymes, which stops influenza virions from being released from the cell | 67%
|
| how do human immunodeficiency viruses (HIV) replicate? | they are retroviruses, so they reverse transcribe their RNA genome into DNA, and insert it into the host cell genome | 67%
|
| how do we use it to treat HIV? | administer a combination of 3 antiviral drugs (typically 1 non-nucleoside reverse transcriptase inhibitor and 2 nucleoside reverse transcriptase inhibitors, plus an integrase inhibitor) | 50%
|
| assembly | 50%
| |
| what are the drugs used in this treatment? | dolutegravir | 50%
|
| expression of virus genome translation/transcription | 50%
| |
| what is the frontline treatment option for HIV? | highly active antiretroviral therapy (HAART) | 50%
|
| lamivudine | 50%
| |
| polymerase inhibitors | 50%
| |
| tenofovir disoproxil | 50%
| |
| how do they replicate? | using DNA polymerase | 50%
|
| virus penetration | 50%
| |
| what is the basic viral replication cycle? | virus adsorbtion | 33%
|
| blocks the virus from fusing to the cell membrane | 17%
| |
| protein synthesis | 17%
| |
| reverse transcriptase inhibitors | 17%
| |
| what are their mechanisms of action? | the drug will bind where the virus attaches, blocking the virus from binding | 17%
|
| blocks the virus from integrating with the host DNA | 0%
|
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