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respiratory drugs - Statistics
General Stats
- This quiz has been taken 11 times
- The average score is 25 of 44
Answer Stats
| Hint | Answer | % Correct |
|---|---|---|
| what are the types of antihistamines used to treat allergic rhinitis? | 1st generation | 83%
|
| 2nd generation | 83%
| |
| what is the one anticholinergic drug used in Australia to treat asthma? | ipratropium | 83%
|
| ipratropium | 83%
| |
| long acting | 83%
| |
| loratadine, fexophenadine, etc | 83%
| |
| what is an example of each? | salbutamol, terbutaline, etc | 83%
|
| what are the 3 types of sympathomimetics used to treat asthma? | short acting | 83%
|
| what kind of molecule is omalizumab? | a recombinant-derived monoclonal antibody | 67%
|
| codeine | 67%
| |
| corticosteroids | 67%
| |
| what is an example of a corticosteroid used to treat asthma? | fluticasone, prednisolone, etc | 67%
|
| what is its mechanism of action? | it binds to immunoglobulin E (IgE) and reduces binding of IgE to its receptor on the surface of basophils, mast cells and dendritic cells | 67%
|
| what are the nasal decongestants used to treat allergic rhinitis? | phenylephrine | 67%
|
| pseudoephedrine | 67%
| |
| salmetrol, bambuterol, etc | 67%
| |
| what is an example? | theophylline, aminophylline | 67%
|
| what is their mechanism of action? | they act on peripheral H1 histamine receptors (in mast cells, endothelium and smooth muscle) to reduce the symptoms of allergic rhinitis | 67%
|
| what is their mechanism of action? | they are a1-adrenergic receptor agonists that cause vasoconstriction and increase mucociliary clearance, therefore decreasing airway resistance | 67%
|
| thought to activate μ and k opioid receptors in the cough centre of the brain | 67%
| |
| thought to activate μ and k opioid receptors in the cough centre of the brain | 67%
| |
| act on central H1 receptors | 50%
| |
| what is omalizumab used to treat? | allergic asthma | 50%
|
| allergic rhinitis | 50%
| |
| what drugs are used to treat COPD? | b-adrenergic agonists | 50%
|
| what is the mechanism of action of each of these? | blocks the generation of leukotrienes from arachidonic acid by inhibiting 5-lipoxygenase | 50%
|
| what are the drugs that treat cough? | dextromethorphan | 50%
|
| what does this do to mast cells? | it limits the degranulation of mast cells, thereby reducing release of pro-inflammatory mediators involved in the allergic response | 50%
|
| what kind of drugs are cromolyn & nedocromil? | mast cell stabilisers | 50%
|
| monteleukast, zafirleukast, & pranleukast | 50%
| |
| pholcodine | 50%
| |
| what is their mechanism of action? | phosphodiesterase inhibitors: competitive enzyme inhibition results in sustained elevation of cAMP or cGMP resulting in bronchodilation | 50%
|
| what do they do? | prevent the release of inflammatory mediators such as histamine | 50%
|
| what receptors do they act on? | selective for peripheral H1 receptors | 50%
|
| what are the leukotriene antagonists used to treat asthma? | zileuton | 50%
|
| what is their mechanism of action? | activation of b2 receptors relaxes smooth muscle in the airways (bronchodilation), without affecting inflammation | 33%
|
| what are their postulated mechanisms of action? | binds to sigma receptors in the cough centre of the brain | 33%
|
| carmoterol, indacaterol, etc | 33%
| |
| what is an example of these? | chlorphenamine, mepyramine, etc | 33%
|
| what kind of drugs are xanthines? | naturally occurring stimulants | 33%
|
| what is their mechanism of action? | they bind to the glucocorticoid receptor to up-regulate expression of several anti-inflammatory proteins as well as down-regulate pro-inflammatory proteins | 33%
|
| they inhibit cysteinyl leukotriene receptor 1 (cysLT1), blocking the action of leukotriene D4 | 33%
| |
| what is its mechanism of action? | works as a non-selective muscarinic receptor antagonist to: - decrease Ach-mediated bronchospasms - reduce irritant-induced mucus secretion - increase ciliary clearance | 33%
|
| ultra long acting | 17%
|
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