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gastrointestinal drugs - Statistics
General Stats
- This quiz has been taken 30 times
- The average score is 7 of 21
Answer Stats
| Hint | Answer | % Correct |
|---|---|---|
| proton pump inhibitors | 63%
| |
| what causes it? (GERD top box, ulcers bottom box) | bacteria (H.pylori) or overuse of NSAIDs | 58%
|
| omeprazole, lansoprazole, etc | 58%
| |
| what are the drug types used to treat GERD & peptic ulcers? | antacids | 53%
|
| what is the pathophysiology of peptic ulcers? | an ulcer in an area where the mucosa is saturated in HCl and pepsin of the gastric juices | 53%
|
| what causes it? (GERD top box, ulcers bottom box) | if there is too much pressure on the stomach or the sphincter muscle is dysfunctional | 47%
|
| binds to E1 G-protein coupled receptors on parietal cells, inhibiting adenyl cyclase and decreasing cAMP, blocking acid production | 37%
| |
| cimetidine, ranitidine, etc | 37%
| |
| H2 receptor antagonists | 32%
| |
| what is the pathophysiology of gastroesophageal reflux disease (GERD)? | occurs when contents of stomach and duodenum backflow into oesophagus, causing inflammation of the oesophageal mucosa (oesophagitis) | 32%
|
| M1 muscarinic receptor antagonism, blocking acetylcholine | 26%
| |
| misoprostol | 26%
| |
| competitively blocks H2 histamine receptors, which stimulate gastric acid secretion from parietal cells, to reduce stomach acidity | 21%
| |
| M1 muscarinic receptor antagonists | 21%
| |
| mucosal strengtheners | 21%
| |
| polymerise in the acid environment of the stomach, then binds to the damaged tissue and forms a protective coating over the ulcer beds | 21%
| |
| irreversibly inhibits the hydrogen-potassium ATPase proton pump that controls H+ secretion from parietal cells, reducing gastric acid production | 16%
| |
| pirenzepine, hyoscyamine, etc | 16%
| |
| sucralfate, bismuth chelate, etc | 16%
| |
| prostaglandins | 11%
| |
| what is the mechanism of action of each? | neutralises stomach acid, thereby increasing pH of stomach and allowing mucous layer time to repair itself | 5%
|
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