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pharmacology - multi choice practice exam - Statistics
General Stats
- This quiz has been taken 100 times
- The average score is 11 of 40
Answer Stats
| Question | Answer | % Correct |
|---|---|---|
| Donepezil is an enzyme inhibitor used in the treatment of Alzheimer’s disease. Which enzyme does it act on? | Acetylcholinesterase | 68%
|
| On which cell type in the stomach does pantoprazole act? | Parietal cells | 61%
|
| Levodopa, a metabolic precursor of dopamine is used as a primary treatment for Parkinsonism. Which levodopa metabolism inhibitor drug is it normally combined with? | Carbidopa | 57%
|
| Which of the following is NOT an effect of insulin on lipids and fat fuel homeostasis? | Increases lipolysis | 50%
|
| Which of the following neurotransmitters does not contribute to mood elevation when levels are raised in neuronal synapses? | Acetylcholine | 46%
|
| Zolpidem (Stilnox) binds to the omega-1 modulatory site found on which receptor? | The GABA-A receptor | 46%
|
| How does galantamine exert its anti-Alzheimers actions? | It enhances the levels of synaptic acetylcholine by inhibiting the acetylcholinesterase enzyme. | 39%
|
| Decrease in the levels of vasopressin (ADH) results in | Diabetes Insipidus | 36%
|
| Which of the following bronchodilators belongs to the anticholinergic class of drugs? | Ipratropium | 36%
|
| How does novocaine exert it’s effects as a local anaesthetic ? | It blocks neuronal sodium ion channels | 36%
|
| Which of the following antidepressant drugs exerts its effects by acting as a monoamine oxidase inhibitor (MAOI)? | Phenelzine | 36%
|
| Which of the following is the definition of pharmacological tolerance? | The decrease in pharmacological effect upon repeated administration of a drug | 36%
|
| How does the anti-asthma drug cromolyn exert its anti-inflammatory action? | It is a mast-cell stabiliser preventing the release of inflammatory mediators such as histamine | 32%
|
| Which of the following is used to reverse an opioid overdose? | Naloxone | 32%
|
| Which of the following is not a common gastrointestinal tract adverse effect associated with NSAIDs such as aspirin? | Constipation | 29%
|
| How does aspirin exert it’s antiplatelet action? | It is a COX inhibitor | 29%
|
| Osmotic diarrhoea is an adverse effect associated with which of the following antacids? | Magnesium hydroxide | 29%
|
| Which enzyme is the molecular target for the anticoagulant, warfarin? | Vitamin K oxide reductase | 29%
|
| Phenylephrine, a nasal decongestant used in the treatment of allergic rhinitis (hayfever), exerts its effects by acting as: | A selective alpha 1 adrenergic receptor agonist | 25%
|
| Which of the following statements is true with regards to the opioid class of drugs? | Opioids decrease the motility and increases the tone of intestinal smooth muscle stopping diarrhoea | 25%
|
| Which of the following statements is TRUE concerning the posterior pituitary gland? | Anti-diuretic hormone is synthesised in the hypothalamus and transported to the posterior pituitary where it is stored | 21%
|
| Anandamide belongs to which class of cannabinoid molecules? | Endocannabinoids | 21%
|
| Which of the following opioids is not present in the opium poppy? | Heroin | 21%
|
| Which of the following drugs can be used to help prevent convulsions in pregnancy? | Magnesium sulphate | 21%
|
| Which of the following is a member of the thiazolidinedione class of insulin sensitisers used in the treatment of type II diabetes? | Pioglitazone | 21%
|
| Paclitaxel is a drug used to treat non-small cell lung cancer. What is its mechanism of action? | It stabilises microtubules by preventing depolymerisation resulting in the inhibition of the normal dynamic reorganisation of the microtubule network essential for cellular functions | 18%
|
| Which of the following monoclonal antibodies is an anti-inflammatory agent used in the treatment of asthma ? | Omalizumab | 18%
|
| Which of the following antibiotic groups does NOT belong to beta lactam class? | Tetracyclines | 18%
|
| Overproduction of growth hormone in an adult leads to? | Acromegaly | 14%
|
| CB1 cannabinoid receptors belong to which class of membrane receptors? | Gi-linked G protein-coupled receptors | 14%
|
| Probenecid is used as a treatment for gout. Probenecid exerts its effects by: | Increases uric acid excretion | 14%
|
| Which of the following human insulin and insulin analogues has the most rapid onset of action | Lispro insulin | 14%
|
| Which of the following statements is FALSE with respect to the H5N1 avian influenza virus? | There is difficulty of transmission between birds halting potential global spread | 14%
|
| Successful molecular therapy has been achieved with a number of genetic diseases. The gene for which enzyme has been successfully introduced into bone marrow as a treatment for patients with severe combined immunodeficiency (bubble boy disease) | Adenosine deaminase | 11%
|
| Which drug class does the anti-cancer drug, bleomycin belong to? | Antibiotic | 11%
|
| Which of the following is TRUE about the anti-influenza drug zanamivir (Relenza)? | It is a neuraminidase inhibitor | 11%
|
| Propylthiouricil is indicated for Graves’ disease. How does it exert its therapeutic effect? | It inhibits synthesis of thyroid hormone by inhibiting the iodination process | 7%
|
| The Oxford-Astra Zeneca vaccine, currently being used in Australia to combat COVID- 19 infections, belongs to which vaccine type? | Viral vector vaccine | 7%
|
| Which of the following is NOT classified as a naked monoclonal antibody for use in cancer therapy? | Gemtuzumab ozogamicin | 4%
|
| Which of the following statements regarding the benzodiazepine class of drugs is UNTRUE? | At high doses BZPs relax the spasticity of skeletal muscle by increasing presynaptic inhibition in the spinal cord via GABAB receptors. | 0%
|
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