Cancer Drugs

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Last updated: May 27, 2024

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Hint	Answer
PI3K inhibitor for blood cancers	idelalisib
PI3K inhibitor for breast cancers	alpelisib
Dual PI3K and mTOR inhibitor	paxalisib
mTOR inhibitor for renal and pancreatic cancers	everolimus
Akt inhibitor for breast cancer	capivaseritib
ADC for HER2+ breast cancer	ado-trastuzumab emtansine
ADC for acute lymphoblastic leukaemia (ALL)	inotuzumab ozogamicin
CDK inhibitor for HER2- and HR+ breast cancer	ribociclib
CDK inhibitor for HER2- and HR+ breast cancer	palbociclib
EGFR and HER1 inhibitor for bowel, neck, and head cancers	cetuximab
VEGF inhibitor, restricting angiogenesis	bevacizumab

Hint	Answer
Targets HER2+ to prevent homodimerisation	trastuzumab
Targets HER2+ to prevent heterodimerisation with HER3	pertuzumab
PD-L1R inhibitor for triple - breast cancer	pembrolizumab
PD-L1 inhibitor for non-small cell lung cancer (NSCL)	durvalumab
BiTE for Muc17+ cancers	vepsitamab
BiTE for CD19+ ALL cancers	blinatumomab
Tri-specific for EpCAM+ cancers	catumaxomab
G12C mutation inhibitor for NSCL cancer	sotorasib
Locks KRAS G12C in inactive form for NSCL cancer	adagrasib
Recruit E3 ligase to KRAS for degradation by ubiquitin	PROTACs

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