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Blood Types
Can you name every blood type?
Hint: All types must end in positive or negative
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Last updated: May 27, 2017
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| First submitted | May 26, 2017 |
| Times taken | 41 |
| Average score | 87.5% | Report this quiz | Report |
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"Rh null" refers to someone who lacks all 5 major antigens of the Rh blood group system- D (commonly called "Rh"), C, E, c, and e.
Clinically, we call this "golden blood" because antibodies to these 5 antigens comprise a majority of red blood cell antibodies that we encounter in routine blood bank testing (ABO/Rh types, antibody screens and identification).
So if you're Rh null your "blood type" (ABO and Rh types) will still react the same way as someone else's, and we would only discover your Rh null status by performing a full phenotype or genotype on your blood sample- something that is not routinely done. We only perform full pheno/genotypes on certain kinds of patients and blood donors to identify and source blood products for patients with these antibodies.
TL;DR "Rh null" is not its own blood type in the classical sense of the term. Someone who is A/B/AB/O negative may also be Rh null. You can't just be Rh null.
Other Rh antigens besides D, C, E, c, and e include V, VS, f, G.
Rh antigens are integral to the structure of the RBC membrane, so interestingly enough, though these donors are unicorns and highly sought after, because of the compromised structure of their RBCs, they can often develop abnormalities like hemolytic anemia. This is just another reason why Rh null donors are so important- because they can only safely receive blood from other ABO-compatible Rh null donors. Theoretically, they could receive Rh-incompatible blood once (insert complicated immunology explanation here), but once they start developing antibodies the blood they receive will be increasingly harder to find until they've developed antibodies to the whole/most of system. *This* is why Rh null donors are so important.