| Portrayed by... | Clue | Character | % Correct |
|---|---|---|---|
| Mike Myers | Evil genius and nemesis of Powers | Dr. Evil | 100%
|
| Verne Troyer | Miniature clone of the above who likes to bite | Mini-Me | 95%
|
| Mike Myers | Morbidly obese Scottish henchman who weighs a metric ton | Fat Bastard | 78%
|
| Seth Green | Son of the evil genius who is perturbed by the fact that his father was absent for so long, and suddenly decided to show up | Scott Evil | 73%
|
| Robert Wagner, Rob Lowe | Second in command to the evil genius who wears an eyepatch | Number 2 | 71%
|
| Michael York | Works for British Intelligence as Austin's controller | Basil Exposition | 68%
|
| Mike Myers | Dutch roller-disco club owner who is the main antagonist in the third film | Goldmember | 63%
|
| Elizabeth Hurley | Powers' partner in the first film who turns out to be a Fembot | Vanessa Kensington | 63%
|
| Mindy Sterling | German attack and defence specialist who shouts her orders extremely loudly | Frau Farbissina | 54%
|
| Beyoncé | Powers' partner in the third series who live in the 1970's | Foxxy Cleopatra | 51%
|
| Heather Graham | CIA agent who is Powers' partner in the second film | Felicity Shagwell | 49%
|
| Persian Cat, Spyhnx | Evil genius' pet Persian cat who looses his fur during the unfreezing process | Mr. Bigglesworth | 46%
|
| Mimi Rogers | Powers' original sidekick back in the 1960s and mother of the above | Mrs. Kensington | 41%
|
| Will Ferrell | Arab fez-wearing henchman who while feeling pain, does not die easily | Mustafa | 41%
|
| Michael Caine | Master spy who is Powers' father | Nigel Powers | 39%
|
| Joe Son | Korean shoe-throwing assassin who tries to strangle Powers | Random Task | 27%
|
| Fred Savage | Mole working for British Intelligence who has a large mole on his face | Number 3 | 12%
|