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1. 1622 – The town of Bucaramanga is founded by Andres Paes de Sotomayor. Bucaramanga is in which South American country ?
2. 1808 – Ludwig van Beethoven conducts and performs four of his pieces in concert at a theatre in which city ?
3. 1851 – What is operated for the first time in India at Roorkee ?
4. 1888 – The Christmas Meeting of 1888, considered to be the official start of which region's independence movement
5. 1890 – Cornwallis Valley Railway begins operation between Kentville and Kingsport in which Canadian province ?
6. 1937 – Which tunnel opens to traffic in New York City ?
7. 1942 – World War II: Adolf Hitler signs the order to develop which weapon ?
8. 1963 – The cruise ship "Lakonia" catches fire 180 miles north of which island with the loss of 128 lives ?
9. 1965 – In the United Kingdom, a speed limit is applied to all rural roads including motorways for the first time. What was the speed limit ?
10. 1974 – The house of which former British Prime Minister is attacked by members of the Provisional IRA ?
11. 1984 – "Subway vigilante" Bernhard Goetz shoots four would-be muggers on an express train in which city ?
12. 1989 – Which Berlin border crossing re-opens after nearly 30 years, effectively ending the division of East and West Germany ?
13. 1997 – Hussein Farrah Aidid relinquishes which disputed title by signing the Cairo Declaration, in Cairo, Egypt ?
14. 2001 – Richard Reid attempts to destroy a passenger airliner by igniting explosives. Where were they hidden ?
15. 2016 – A study finds the VSV-EBOV vaccine is between 70-100% effective, and thus making it the first proven vaccine against which disease ?