Biggest cities by language A-Z (Spanish)

For each letter, give the largest city by population that speaks Spanish natively.
Population data from Wikipedia
City boundaries only - metro population not included
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xahmie
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Last updated: January 1, 2026
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First submittedJanuary 1, 2026
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Population
Region
Hint
Answer
A
949,000
Mexico
named for natural hot springs, famous for hosting the massive Feria de San Marcos
Aguascalientes
B
8 million
South America
home to the world-renowned Gold Museum and is often called the “Athens of South America”
Bogotá
C
3.2 million
South America
this capital city is the birthplace of Simón Bolívar
Caracas
D
616,000
Mexico
“Land of Cinema” filming location for hundreds of Western movies
Durango
E
1.6 million
Mexico
features the Mexicable, a public transit cable car system
Ecatepec de Morelos
F
308,000
South America
“Sweet City” for its famous obleas (wafer sandwiches with caramel) and its proximity to the Chicamocha Canyon
Floridablanca
G
2.7 million
South America
gateway to the Galápagos Islands, main port of its country
Guayaquil
H
2.1 million
Caribbean
famous for its vintage American cars, Spanish colonial architecture, and the historic Malecón seawall
Havana
I
491,000
South America
largest city in the world unreachable by road
Iquitos
J
1.5 million
Mexico
major industrial hub often cited as the birthplace of the burrito
Ciudad Juárez
K
140,000
Mexico
regionally famous for its traditional cuisine, specifically its reputation as the “Capital of the Panucho”
Kanasín
L
10 million
South America
“City of Kings” widely considered the gastronomy capital of the world
Lima
M
9.2 million
Mexico
built on the ruins of the Aztec capital Tenochtitlán, famous for its “sinking” cathedral
Mexico City
N
1 million
Mexico
named after the “Poet King” of the Texcoco people
Nezahualcóyotl
Ñ
267,000
South America
Chilean city known for its bohemian vibe and as the home of the National Stadium
Ñuñoa
O
259,000
Mexico
renowned for its Seven Moles, mezcal, and the nearby Zapotec ruins of Monte Albán
Oaxaca
P
1.7 million
Mexico
famous for its colorful Talavera pottery and as the site of the 1862 battle that inspired the “Cinco de Mayo” holiday
Puebla
Q
1.8 million
South America
capital city of Ecuador
Quito
R
1.3 million
South America
birthplace of Lionel Messi and Che Guevara
Rosario
S
6.3 million
South America
this capital features the Costanera Center, the tallest building in South America
Santiago de Chile
T
1.9 million
Mexico
“Gateway to Mexico” hosting the world’s busiest land border crossing
Tijuana
U
300,000
Mexico
“Avocado Capital of the World” home to the only national park located inside a city's limits in Mexico
Uruapan
V
1.6 million
South America
famous for its homonymous lake and its history as a three-time capital of its country
Valencia, Venezuela
W
63,000
Central America
cultural hub of the Miskito indigenous people
Waspam, Nicaragua
X
489,000
Mexico
“City of Flowers” namesake of the Jalapeño pepper
Xalapa
Y
120,000
South America
Venezuelan town that is a major center for the Yaracuy region’s sugar cane industry
Yaritagua, Venezuela
Z
1.5 million
Mexico
famous for its Basilica and is one of the most affluent cultural hubs in western Mexico
Zapopan
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