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Synthetic Routes - OCR A Level Chemistry

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Last updated: June 17, 2023
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First submittedJune 17, 2023
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1. What reagents do you use to go from Alkene to Alkane?
Ethanolic NH3
Acidified potassium dichromate / reflux
NaHCO3
H2 / Ni
2. What reagents do you use to go from Alkene to Alcohol?
H2O(g) / H3PO4
H2 / Ni
Smirnoff's reagent
HCN
3. What reagents for Alkane to Haloalkane?
Radical substitution: X2 / UV light
KCN / Uranium
Uranium
NaX / H2SO4 / heat
4. Haloalkane to Alcohol?
NaOH / heat
HCl / heat
NaBH4
KCN / Ununoctium
5. Alcohol to Alkene?
NaBH4
Ethanolic KCN
X2 / UV Light
H2SO4 / heat
6. You reflux tertiary alcohol + acidified potassium dichromate What do you get?
Carboxylic acid
Aldehyde
Ketone
No change
7. Butan-1-ol is distilled with acidified potassium dichromate. What do you get?
Butanone
Butanoic Acid
Butanal
But-2-ene
8. Butan-2-one is reacted with Z to form an Butan-2-ol. What is Z?
NaBH4
H2SO4 / reflux
HCN
Cinnamaldehyde
9. Walter is doing a PAG, and needs to make methanoyl chloride from methanol. What reagents does he use?
NaBH4
1. Reflux with acidified potassium dichromate THEN 2. Add SOCl2
Reflux with acidified potassium dichromate
Add SOCl2
10. What can Walter NOT make, in one step, using an Acyl Chloride?
Carboxylate salt, by adding NaOH
Ester, by adding alcohol
Primary amide, by adding ammonia
Secondary amide, by adding a primary amine
11. How can you reduce a nitrile to an amine?
H2 / Ni
UV and X2
ethanolic KCN
ethanolic NH3
12. Walter wants to make a secondary amine from a primary amine. What reagents does he use?
CH3Cl + NH3 / Ethanol
HNO3 / H2SO4
CH3Cl + KCN / Ethanol
CH3Cl + CH2(Cl)CH2CH(CH3)NH2 / Ethanol
13. In the last step of Walter's synthesis, he is alkylating benzene. What reagent and catalyst does he use, and what is the name of this process?
RCl / AlBr3 / Friedel-Crafts Alkylation
RCl / AlCl3 / Friedel-Crafts Alkylation
RCl / AlCl3 / Schade-Havertz Acylation
RNH2 / AlCl3 / Friedel-Crafts Alkylation
14. NO2 to NH2?
Sb + HCl then add NaOH, to deprotonate NH3+
Sb + HCl then add NaS2O3
Sn + HCl then add NaS2O3
Sn + HCl then add NaOH, to deprotonate NH3+
15. I am nitrating phenol What reagents do I need and what position will the substitution occur?
HNO3 only, 3
HNO3 / H2SO4, 2 and 4
HNO3 only, 2 and 4
HNO3 / H2SO4, 3
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