Drug Interactions - Statistics

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  • This quiz has been taken 5 times
  • The average score is 3 of 15
Answer Stats
Hint Answer % Correct
Does a competetive antagonist have efficacy? No
100%
When a competetive antagonist is added, what direction is an agonists log concentration/response curve shifted in? Right
60%
How many membrane spanning alpha helices do G protein coupled receptors have? 7
40%
Whereas what is the term used to describe the degree to which a molecule has a tendency to bind to another? Affinity
40%
What is the word used to describe, the relationship between the amount of receptor occupied by a drug and the size of the response produced? Efficacy
40%
What is the name given to the concentration of agonist that causes 50% of the maximum responce? EC50
20%
What receptor is benzilylcholine mustard an antagonist of? Muscarinic
20%
What in equations is used to represent the maximal of this type of binding? Bmax
0%
Which membrane bound protein kinase does diacylglycerol (DAG) stimulate? C
0%
What toxin effects G protein coupled receptors by causing ADP-ribosylation of alpha-s, inhibiting GTPase activity keeping adenylyl cyclase activated? Cholera
0%
What is the name given to the answer from this equation. (concentration of agonist with competitive antagonist required to get set response/concentration of agonist without antagonist getting the same response)? Dose ratio
0%
What is used to represent the concentration of unlabelled drug required to inhibit 50% of specific binding of a radioligand? IC50
0%
What technique allows recording of the behaviour of a single receptor? Patch-clamp
0%
The binding of a radioligand (total binding) is made up of two parts, what is the saturable component? Specific binding
0%
What is the name of a sequence of experiments used to determine the strength of a group of structurally similar compounds? Structure activity series
0%
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