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Drug-receptor interactions - Statistics
General Stats
- This quiz has been taken 5 times
- The average score is 3 of 16
Answer Stats
| Hint | Answer | % Correct |
|---|---|---|
| What type of molecule when it binds to a receptor produces (increases) a response? | Agonist | 100%
|
| What about a ligand determines how much of it binds to a receptor given its concentration? | Affinity | 75%
|
| Addition of a competetive antagonist will shift a log concentration/response curve in what direction? | Right | 75%
|
| What is the relationship between the amount of receptors occupied and the size of the response? | Efficacy | 25%
|
| This phenomenon has 2 key forms for Beta adrenoreceptors, heterologous and homologous. In heterologous PKA phosophorylates the receptor but is not specific, in homologous, what enzyme phosphorylates it? | Beta-adrenoreceptor kinase/BARK | 0%
|
| After this the binding of what protein uncouples the receptor? | Beta arrestin | 0%
|
| What is it called when a receptor requires more than one molecule binding to be activated? | Co-operativity | 0%
|
| What phenomenon is seen when after a prolonged exposure to an agonist the receptor is prevented from producing its normal effect? | Desensitization | 0%
|
| What type of molecules are used to switch the channels between modes (0=channel not open, 1=channel opening in bursts, 2=very long openings)? | Dihydropyridines/DHP | 0%
|
| Three processes are involved in this phenomenon uncoupling, sequestration and last? | Down-regulation | 0%
|
| Which type of this phenomenon occurs with high concentrations of ligand? | Homologous | 0%
|
| In alphabetical order what are the three types of voltage gated Ca2+ channels found in muscle? | L, N and T | 0%
|
| What molecule does cAMP produced by adenyly cyclase control cell functions through? | Protein Kinase A/PKA | 0%
|
| A sequence of experiments to determine the relative potency of a group of structurally related compounds is a what? | Structure activity series | 0%
|
| What type of receptor sometimes requires dimerization in order to autophosphorylate? | Tyrosine kinase | 0%
|
| What is it called if a drug is more effective when the target is being used more frequently? | Use dependence | 0%
|
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