| Hint | Answer | % Correct |
|---|---|---|
| Rerolls Isaac's active item every time it's used | 'M | 88%
|
| 50% to get drop after destroying a poop | Petrified Poop | 88%
|
| Spawns a coin after taking damage | Swallowed Penny | 79%
|
| Pulls coins towards Isaac | Broken Magnet | 71%
|
| +1 fire rate | Cancer | 71%
|
| -0.5 shot speed | Lazy Worm | 71%
|
| Respawns Isaac as The Lost upon death | Missing Poster | 63%
|
| Prevents active items from spawning | No! | 63%
|
| Isaac's tears get a random worm effect every 3 seconds | Rainbow Worm | 63%
|
| Has a 22.22% chance to revive Isaac as ??? | Broken Ankh | 58%
|
| Triggers Teleport! when an active item is used | Broken Remote | 58%
|
| When Isaac has the same amount of coin, bombs, & keys, drops will be doubled | Equality! | 58%
|
| Drops a black heart when Isaac is at a half heart 3 times | Monkey Paw | 58%
|
| Immunity to floor spikes | Callus | 54%
|
| +2 damage up | Curved Horn | 54%
|
| Grants a random trinket effect every room | Error | 54%
|
| Spawns a locust that explodes on impact | Locust of War | 54%
|
| 10% chance of replacing the room clear reward with a bomb | Match Stick | 54%
|
| Doubles the chance of champion enemies | Purple Heart | 54%
|
| Special rocks will flash upon entering a room | Shiny Rock | 54%
|
| Fully recharges active item at the second to last charge | AAA Battery | 50%
|
| Grants a chance to get a half heart from picking up a coin | Bloody Penny | 50%
|
| Grants a chance to drop a bomb after collecting a coin | Burnt Penny | 50%
|
| Has a chance to confuse all enemies in a room | Faded Polaroid | 50%
|
| Grants a chance to drop a key after picking up a coin | Flat Penny | 50%
|
| When entering a room, you get a 25% chance of getting a mushroom effect | Liberty Cap | 50%
|
| Rocks have a 33% to drop a coin | Lucky Rock | 50%
|
| +1 luck | Lucky Toe | 50%
|
| Mom's foot stomps randomly every 20 seconds | Mom's Toenail | 50%
|
| Isaac's tears pulsate | Pulse Worm | 50%
|
| Replaces all chests with Red Chests | The Left Hand | 50%
|
| 0.4 tears, Spectral tears, & tears move in a wave like pattern | Wiggle Worm | 50%
|
| Gives a once per floor holy mantle | Wooden Cross | 50%
|
| When Isaac picks up coins he farts | Butt Penny | 46%
|
| Isaac will be teleported to a random room after being hit and left at half a heart | Cursed Skull | 46%
|
| Spawns a blue fly after taking damage | Fish Head | 46%
|
| +0.15 speed | Goat Hoof | 46%
|
| Spawns a locust that does 4x Isaac's damage | Locust of Death | 46%
|
| Spawns a locust that slows the enemy | Locust of Famine | 46%
|
| Causes a restock machine to spawn in treasure rooms | Pay to Win | 46%
|
| +10 luck | Perfection | 46%
|
| Increases the chance of angel rooms & bible spawns | Rosary Bead | 46%
|
| Converts troll bombs into normal bombs | Safety Scissors | 46%
|
| Makes all shop item free once then destroys trinket | Store Credit | 46%
|
| Removes 15% HP of enemies that have over 60 HP, can't remove | Tick | 46%
|
| Entering a new room can sometimes set enemies on fire | A Lighter | 42%
|
| Adds +40 damage to The Necronomicon | A Missing Page | 42%
|
| Increases the chances of eternal hears appearing | Bible Tract | 42%
|
| Treasure rooms can appear in womb & utero | Bloody Crown | 42%
|
| Bombs leave green creep when placed | Bob's Bladder | 42%
|
| 25% to grant a random syringe every new room | Broken Syringe | 42%
|
| 50% chance to activate the effects of dice when taking damage | Cracked Dice | 42%
|
| Grants a stat boost when an active item is completely uncharged | Dim Bulb | 42%
|
| Familiars will stay in one place | Duct Tape | 42%
|
| Any blue flies or locusts will be doubled | Fish Tail | 42%
|
| Spawns a familiar that shoots piercing tears that does 3.5 DMG a shoot | Isaac's Head | 42%
|
| Spawns 1-4 locusts that die upon impact | Locust of Conquest | 42%
|
| Spawns a locust that gives enemies a poison effect | Locust of Pestilence | 42%
|
| Isaac has a chance to poop or fart every 30 seconds | Mysterious Candy | 42%
|
| Gold chests can be opened for free | Paper Clip | 42%
|
| Spawns a blue fly every time a coin is picked up | Rotten Penny | 42%
|
| 10% chance of replacing the room clear reward with a card | Ace of Spades | 38%
|
| Grants Isaac's familiars homing shots | Baby-Bender | 38%
|
| Has a chance to fire a black tooth that does 2x Isaac's damage | Black Tooth | 38%
|
| Causes poops to explode when destroyed | Brown Cap | 38%
|
| Active items drop onto a pedestal when used | Butter! | 38%
|
| 5% for the Gamekid effect to happen after taking damage | Cartridge | 38%
|
| Familiars stay closer to Isaac | Child Leash | 38%
|
| Angel statues will drop angel items instead of key pieces | Filigree Feather | 38%
|
| Removes all spikes | Flat File | 38%
|
| Donating to a donation machine can do random things like return your coin | Karma | 38%
|
| Uses Isaac's active item right before taking damage | Panic Button | 38%
|
| Isaac has a 20% chance of getting a +1.8 damage up from taking damage | Red Patch | 38%
|
| Gives a chance to drop half a soul heart when collecting coins | Blessed Penny | 33%
|
| Picking up a coin has a chance to increase its value by 1 | Counterfeit Penny | 33%
|
| Gives stat boosts if the stats are above base value | Cracked Crown | 33%
|
| Makes the last door Isaac went through stay open | Door Stop | 33%
|
| 25% chance to gain another consumable after use (pill, card, etc.) | Endless Nameless | 33%
|
| Gives tears an oblong appearance & slight knockback | Flat Worm | 33%
|
| Adds a luck-based chance to fire a tooth shot | Jawbreaker | 33%
|
| 1/3 chance to get a random mom item for the room | Mom's Lock | 33%
|
| +0.4 tears, +1.5 range and Isaac's tears travel in a large spiral | Ouroboros Worm | 33%
|
| Chance to shoot poison shots | Pinky Eye | 33%
|
| 0.4 tears, Spectral tears, & tears move in a fast spiral | Ring Worm | 33%
|
| 10% chance of replacing the room clear reward with a key | Rusted Key | 33%
|
| When an enemy dies, Isaac gets a 1/15 chance to get a +0.5 damage up | Samson's Lock | 33%
|
| Shops no longer need to be openned with keys | Store Key | 33%
|
| 10% chance to fire bouncing tears | Super Ball | 33%
|
| +3 range | Tape Worm | 33%
|
| After taking 6-12 hits, Isaac spawns a familiar that blocks shots | Tonsil | 33%
|
| 15% chance to make certain fly enemies harmless for each room | Used Diaper | 33%
|
| Getting hit by an explosion gives a 33% chance to spawn a drop | Walnut | 33%
|
| Killing an enemy has a 5% chance to grant flight for the room | Bat Wing | 29%
|
| Doubles invincibility frames after taking damage | Blind Rage | 29%
|
| Increases knockback | Blister | 29%
|
| Isaac's tears snap 90 degrees to hit missed targets | Brain Worm | 29%
|
| 50% to add a blind item to treasure rooms | Broken Glasses | 29%
|
| Grants a 25% chance to gain The Compass effect starting a new floor. | Cain's Eye | 29%
|
| 10% chance of changing the room clear reward to a heart | Child's Heart | 29%
|
| Teleports Isaac to random room when picking up a coin | Cursed Penny | 29%
|
| Replaces room clear rewards with keys 80% of the time | Daemon's Tail | 29%
|
| Replaces treasure rooms with special red treasure rooms | Devil's Crown | 29%
|
| When an enemy dies, there is a luck-based chance Dead Bird spawns | Eve's Bird Foot | 29%
|
| Treasure rooms and shops now appear on Cathedral | Holy Crown | 29%
|
| Makes devil deals cost 1 red heart container | Judas' Tongue | 29%
|
| Contributes to Guppy transformation | Kid's Drawing | 29%
|
| Isaac has a chance to spawn blue spiders every 30 seconds in an uncleared room | Louse | 29%
|
| Grants an eternal heart at the start of every floor | Maggy's Faith | 29%
|
| Entering a new room has a 50% of granting a random passive item for the rest of the room | Modeling Clay | 29%
|
| Using a key to unlock doors will heal Isaac for a half heart | Mom's Locket | 29%
|
| Has a chance to mimic 4 different paper-based items | Mysterious Paper | 29%
|
| Doubles the duration of most status effects | Second Hand | 29%
|
| Grants a shield for 1 second after killing an enemy | Sigil of Baphomet | 29%
|
| Increased chance to reveal crawl spaces when rocks are broken | Stud Finder | 29%
|
| Attracts enemies and pickups towards Isaac | Super Magnet | 29%
|
| When Isaac enters a room with half a red hear, Little Steven will spawn | Umbilical Cord | 29%
|
| +0.5 shot speed | Whip Worm | 29%
|
| Allows black markets and shops to sell items from the baby shop pool | Adoption Papers | 25%
|
| Picking up red hearts has a 50% to spawn blue spiders instead | Apple of Sodom | 25%
|
| Upon taking damage, there's a 5% to spawn the item Lunch | Bag Lunch | 25%
|
| +0.5 damage up for each evil item you have | Black Feather | 25%
|
| Rooms that require coins or keys now teleport Isaac to a blue room that acts as a seperation between the two rooms | Blue Key | 25%
|
| Doors that require pickups to open can be opened with explosions | Broken Padlock | 25%
|
| Picking up coins has a chance to charge your active item | Charged Penny | 25%
|
| Causes red hearts to be taken before soul & black hearts | Crow Heart | 25%
|
| 50% chance when taking damage to get a one time use dice item | Dice Bag | 25%
|
| Doubles familiar's fire rate | Forgotten Lullaby | 25%
|
| Spawns a familiar that mimics Isaac's inputs but dies in one hit and spawns at the next floor | Found Soul | 25%
|
| 15% chance for Treasure rooms to contain 2 pedestals | Golden Horseshoe | 25%
|
| +0.4 tears, +1.5 range, Spectral, & tears shift from left to right | Hook Worm | 25%
|
| Upon entering a room, enemies have a 20% to be petrified and frozen when killed | Ice Cube | 25%
|
| Grants a luck-based healing effect after clearing a room | Isaac's Fork | 25%
|
| 50% for items that cost hearts to cost money | Keeper's Bargain | 25%
|
| Increases the radius of creep | Lost Cork | 25%
|
| 5% chance for any heart to become a soul heart | Mom's Pearl | 25%
|
| +1 Heart container | Mother's Kiss | 25%
|
| 10% chance to fire booger tears | Nose Goblin | 25%
|
| Starting at Womb, coins and keys will be replaced with drops like bombs & cards | Nuh Uh! | 25%
|
| 50/50 for a chest to contain double pickups or an attack fly | Poker Chip | 25%
|
| Chance to shoot piercing and spectral tears | Push Pin | 25%
|
| Placing a bomb will place an additional bomb for free | Ring Cap | 25%
|
| 10% chance of replacing the room clear reward with a pill | Safety Cap | 25%
|
| Shops can appear in womb & utero | Silver Dollar | 25%
|
| Traveling to a new floor heals 50% of Isaac's red hearts | Stem Cell | 25%
|
| Every 15 shots Isaac will fire an Ipecac + My Reflection tear | Torn Card | 25%
|
| Grants a stat boost when an active item is fully charged | Vibrant Bulb | 25%
|
| Upon taking damage, there is a 5% chance to spawn a random item | Wish Bone | 25%
|
| Clearing a room has a chance to turn Isaac into Azazel | Azazel's Stump | 21%
|
| Doubles chances of black hearts appearing | Black Lipstick | 21%
|
| Grants a chance for a 7 Seals locust to spawn when an enemy is killed | Cricket Leg | 21%
|
| Spawns a friendly dip upon clearing a room | Dingle Berry | 21%
|
| Causes electric shocks to arc between Isaac's familiars | Extension Cord | 21%
|
| Entering a new floor will generate an additional secret room | Fragmented Card | 21%
|
| Increases the size and radius of Isaac's farts | Gigante Bean | 21%
|
| Fully recharges the active item when entering a boss room | Hairpin | 21%
|
| Destroying poop will spawn a blue fly | Lil Larva | 21%
|
| +10% devil/angel chance, prevents Krampus from spawning in devil deals | Number Magnet | 21%
|
| Prevents active items from charging normally, and instead can spawn a Lil' Battery familiar | Old Capacitor | 21%
|
| Familiars are now controlled by Isaac's inputs | RC Remote | 21%
|
| Prevents Greed and Super Greed from spawning in shops and secret rooms | Rib of Greed | 21%
|
| Isaac's bomb explodes faster | Short Fuse | 21%
|
| Isaac has a 50% of exploding after taking damage | Swallowed M80 | 21%
|
| Increases the chance of luck-based tears (+4 luck) | Teardrop Charm | 21%
|
| +15% planetarium chance, planetariums now spawn on Womb and Corpse | Telescope Lens | 21%
|
| Entering a room has a 50% to duplicate one of Isaac's familiar | The Twins | 21%
|
| Has a chance to spawn a random battery after clearing a room | Watch Battery | 21%
|
| Can be exhanged for a devil item, once used the trinket will vanish | Your Soul | 21%
|
| Spawns an Abyss locust with a 1.5x damage multiplier | Apollyon's Best Friend | 17%
|
| 10% to drop a bomb after using a bomb | Blasting Cap | 17%
|
| Adds a luck-based chance to slow down enemies | Chewed Pen | 17%
|
| Clearing a room has a 33% chance to open a red room | Crystal Key | 17%
|
| Grants a bone heart at the start of every floor | Hollow Heart | 17%
|
| Spawns a Sumptorium clot | Lil Clot | 17%
|
| Spawns a sack at the start of every floor | Lucky Sack | 17%
|
| Gives a chance for poop to turn into black poop | Meconium | 17%
|
| Clearing a room has a chance to spawn a friendly Bony | Polished Bone | 17%
|
| Spawns a familiar that floats around the room and fire spectral & homing tears | ???'s Soul | 17%
|
| Unlocks a passageway to blue womb, can be used with Pandora's box | Strange Key | 17%
|
| Spawns a chest after the challenge room and an extra item from the boss trap room | Temporary Tattoo | 17%
|
| Treasure rooms and shops can spawn on Sheol | Wicked Crown | 17%
|
| Grants a 4% chance to gain a bone heart after taking damage | Finger Bone | 13%
|
| Familars now orbit around Isaac | Friendship Necklace | 13%
|
| +1 key, all new chests that spawn will become golden chests | Gilded Key | 13%
|
| When Isaac uses an active item, a secondary random active item will trigger along with it | Expansion Pack | 8%
|
| Entering a new floor can spawn 4 pickups that were left on the previous floor | Myosotis | 8%
|
| Isaac drops two random pickups from his inventory upon taking damage | Torn Pocket | 8%
|
| Spawns 5 wisps after entering an angel room | Beth's Essense | 4%
|
| Spawns 4 Book of Virtues wisps at the start of the floor | Beth's Fate | 4%
|