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Hint
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Answer
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Spawns a coin after taking damage
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Swallowed Penny
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50% to get drop after destroying a poop
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Petrified Poop
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Fully recharges active item at the second to last charge
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AAA Battery
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Triggers Teleport! when an active item is used
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Broken Remote
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Doubles the chance of champion enemies
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Purple Heart
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Pulls coins towards Isaac
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Broken Magnet
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Increases the chance of angel rooms & bible spawns
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Rosary Bead
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5% for the Gamekid effect to happen after taking damage
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Cartridge
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Isaac's tears pulsate
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Pulse Worm
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0.4 tears, Spectral tears, & tears move in a wave like pattern
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Wiggle Worm
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0.4 tears, Spectral tears, & tears move in a fast spiral
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Ring Worm
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Gives tears an oblong appearance & slight knockback
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Flat Worm
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Makes all shop item free once then destroys trinket
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Store Credit
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Immunity to floor spikes
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Callus
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Rocks have a 33% to drop a coin
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Lucky Rock
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Mom's foot stomps randomly every 20 seconds
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Mom's Toenail
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Doubles chances of black hearts appearing
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Black Lipstick
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Increases the chances of eternal hears appearing
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Bible Tract
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Gold chests can be opened for free
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Paper Clip
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Drops a black heart when Isaac is at a half heart 3 times
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Monkey Paw
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Has a chance to mimic 4 different paper-based items
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Mysterious Paper
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Replaces room clear rewards with keys 80% of the time
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Daemon's Tail
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Respawns Isaac as The Lost upon death
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Missing Poster
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When Isaac picks up coins he farts
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Butt Penny
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Isaac has a chance to poop or fart every 30 seconds
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Mysterious Candy
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+0.4 tears, +1.5 range, Spectral, & tears shift from left to right
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Hook Worm
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+0.5 shot speed
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Whip Worm
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Has a 22.22% chance to revive Isaac as ???
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Broken Ankh
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Spawns a blue fly after taking damage
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Fish Head
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Chance to shoot poison shots
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Pinky Eye
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Chance to shoot piercing and spectral tears
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Push Pin
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When entering a room, you get a 25% chance of getting a mushroom effect
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Liberty Cap
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When Isaac enters a room with half a red hear, Little Steven will spawn
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Umbilical Cord
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10% chance of changing the room clear reward to a heart
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Child's Heart
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+2 damage up
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Curved Horn
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10% chance of replacing the room clear reward with a key
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Rusted Key
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+0.15 speed
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Goat Hoof
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5% chance for any heart to become a soul heart
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Mom's Pearl
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+1 fire rate
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Cancer
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Isaac has a 20% chance of getting a +1.8 damage up from taking damage
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Red Patch
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10% chance of replacing the room clear reward with a bomb
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Match Stick
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+1 luck
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Lucky Toe
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Isaac will be teleported to a random room after being hit and left at half a heart
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Cursed Skull
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10% chance of replacing the room clear reward with a pill
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Safety Cap
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10% chance of replacing the room clear reward with a card
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Ace of Spades
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Grants a luck-based healing effect after clearing a room
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Isaac's Fork
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Adds +40 damage to The Necronomicon
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A Missing Page
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Grants a chance to get a half heart from picking up a coin
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Bloody Penny
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Grants a chance to drop a bomb after collecting a coin
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Burnt Penny
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Grants a chance to drop a key after picking up a coin
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Flat Penny
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Picking up a coin has a chance to increase its value by 1
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Counterfeit Penny
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Removes 15% HP of enemies that have over 60 HP, can't remove
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Tick
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Spawns a familiar that shoots piercing tears that does 3.5 DMG a shoot
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Isaac's Head
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Grants an eternal heart at the start of every floor
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Maggy's Faith
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Makes devil deals cost 1 red heart container
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Judas' Tongue
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Spawns a familiar that floats around the room and fire spectral & homing tears
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???'s Soul
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When an enemy dies, Isaac gets a 1/15 chance to get a +0.5 damage up
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Samson's Lock
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Grants a 25% chance to gain The Compass effect starting a new floor.
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Cain's Eye
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When an enemy dies, there is a luck-based chance Dead Bird spawns
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Eve's Bird Foot
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Replaces all chests with Red Chests
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The Left Hand
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Special rocks will flash upon entering a room
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Shiny Rock
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Converts troll bombs into normal bombs
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Safety Scissors
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Isaac's tears get a random worm effect every 3 seconds
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Rainbow Worm
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+3 range
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Tape Worm
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-0.5 shot speed
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Lazy Worm
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50% chance to activate the effects of dice when taking damage
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Cracked Dice
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Attracts enemies and pickups towards Isaac
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Super Magnet
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Has a chance to confuse all enemies in a room
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Faded Polaroid
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Isaac has a chance to spawn blue spiders every 30 seconds in an uncleared room
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Louse
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Bombs leave green creep when placed
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Bob's Bladder
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Has a chance to spawn a random battery after clearing a room
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Watch Battery
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10% to drop a bomb after using a bomb
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Blasting Cap
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Increased chance to reveal crawl spaces when rocks are broken
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Stud Finder
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Grants a random trinket effect every room
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Error
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50/50 for a chest to contain double pickups or an attack fly
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Poker Chip
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Increases knockback
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Blister
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Doubles the duration of most status effects
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Second Hand
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25% chance to gain another consumable after use (pill, card, etc.)
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Endless Nameless
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+0.5 damage up for each evil item you have
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Black Feather
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Doubles invincibility frames after taking damage
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Blind Rage
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15% chance for Treasure rooms to contain 2 pedestals
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Golden Horseshoe
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Shops no longer need to be openned with keys
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Store Key
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Prevents Greed and Super Greed from spawning in shops and secret rooms
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Rib of Greed
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Donating to a donation machine can do random things like return your coin
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Karma
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Destroying poop will spawn a blue fly
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Lil Larva
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Using a key to unlock doors will heal Isaac for a half heart
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Mom's Locket
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Prevents active items from spawning
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No!
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Familiars stay closer to Isaac
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Child Leash
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Causes poops to explode when destroyed
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Brown Cap
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Gives a chance for poop to turn into black poop
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Meconium
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Gives stat boosts if the stats are above base value
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Cracked Crown
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15% chance to make certain fly enemies harmless for each room
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Used Diaper
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Any blue flies or locusts will be doubled
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Fish Tail
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Has a chance to fire a black tooth that does 2x Isaac's damage
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Black Tooth
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+0.4 tears, +1.5 range and Isaac's tears travel in a large spiral
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Ouroboros Worm
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After taking 6-12 hits, Isaac spawns a familiar that blocks shots
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Tonsil
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10% chance to fire booger tears
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Nose Goblin
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10% chance to fire bouncing tears
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Super Ball
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Grants a stat boost when an active item is fully charged
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Vibrant Bulb
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Grants a stat boost when an active item is completely uncharged
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Dim Bulb
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Entering a new floor will generate an additional secret room
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Fragmented Card
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When Isaac has the same amount of coin, bombs, & keys, drops will be doubled
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Equality!
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Upon taking damage, there is a 5% chance to spawn a random item
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Wish Bone
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Upon taking damage, there's a 5% to spawn the item Lunch
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Bag Lunch
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Increases the radius of creep
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Lost Cork
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Causes red hearts to be taken before soul & black hearts
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Crow Heart
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Getting hit by an explosion gives a 33% chance to spawn a drop
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Walnut
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Familiars will stay in one place
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Duct Tape
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Shops can appear in womb & utero
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Silver Dollar
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Treasure rooms can appear in womb & utero
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Bloody Crown
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Causes a restock machine to spawn in treasure rooms
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Pay to Win
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Spawns a locust that explodes on impact
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Locust of War
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Spawns a locust that gives enemies a poison effect
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Locust of Pestilence
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Spawns a locust that slows the enemy
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Locust of Famine
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Spawns a locust that does 4x Isaac's damage
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Locust of Death
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Spawns 1-4 locusts that die upon impact
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Locust of Conquest
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Killing an enemy has a 5% chance to grant flight for the room
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Bat Wing
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Traveling to a new floor heals 50% of Isaac's red hearts
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Stem Cell
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Fully recharges the active item when entering a boss room
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Hairpin
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Gives a once per floor holy mantle
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Wooden Cross
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Active items drop onto a pedestal when used
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Butter!
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Angel statues will drop angel items instead of key pieces
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Filigree Feather
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Makes the last door Isaac went through stay open
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Door Stop
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Causes electric shocks to arc between Isaac's familiars
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Extension Cord
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Spawns a blue fly every time a coin is picked up
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Rotten Penny
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Grants Isaac's familiars homing shots
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Baby-Bender
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Grants a 4% chance to gain a bone heart after taking damage
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Finger Bone
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Adds a luck-based chance to fire a tooth shot
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Jawbreaker
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Adds a luck-based chance to slow down enemies
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Chewed Pen
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Gives a chance to drop half a soul heart when collecting coins
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Blessed Penny
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25% to grant a random syringe every new room
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Broken Syringe
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Isaac's bomb explodes faster
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Short Fuse
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Increases the size and radius of Isaac's farts
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Gigante Bean
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Entering a new room can sometimes set enemies on fire
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A Lighter
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Doors that require pickups to open can be opened with explosions
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Broken Padlock
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Entering a new floor can spawn 4 pickups that were left on the previous floor
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Myosotis
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Rerolls Isaac's active item every time it's used
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'M
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Increases the chance of luck-based tears (+4 luck)
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Teardrop Charm
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Picking up red hearts has a 50% to spawn blue spiders instead
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Apple of Sodom
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Doubles familiar's fire rate
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Forgotten Lullaby
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Spawns 4 Book of Virtues wisps at the start of the floor
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Beth's Fate
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Prevents active items from charging normally, and instead can spawn a Lil' Battery familiar
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Old Capacitor
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Isaac's tears snap 90 degrees to hit missed targets
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Brain Worm
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+10 luck
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Perfection
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Replaces treasure rooms with special red treasure rooms
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Devil's Crown
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Picking up coins has a chance to charge your active item
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Charged Penny
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Familars now orbit around Isaac
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Friendship Necklace
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Uses Isaac's active item right before taking damage
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Panic Button
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Rooms that require coins or keys now teleport Isaac to a blue room that acts as a seperation between the two rooms
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Blue Key
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Removes all spikes
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Flat File
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+15% planetarium chance, planetariums now spawn on Womb and Corpse
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Telescope Lens
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1/3 chance to get a random mom item for the room
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Mom's Lock
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50% chance when taking damage to get a one time use dice item
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Dice Bag
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Treasure rooms and shops now appear on Cathedral
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Holy Crown
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+1 Heart container
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Mother's Kiss
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Every 15 shots Isaac will fire an Ipecac + My Reflection tear
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Torn Card
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Isaac drops two random pickups from his inventory upon taking damage
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Torn Pocket
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+1 key, all new chests that spawn will become golden chests
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Gilded Key
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Spawns a sack at the start of every floor
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Lucky Sack
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Treasure rooms and shops can spawn on Sheol
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Wicked Crown
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Clearing a room has a chance to turn Isaac into Azazel
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Azazel's Stump
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Spawns a friendly dip upon clearing a room
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Dingle Berry
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Placing a bomb will place an additional bomb for free
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Ring Cap
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Starting at Womb, coins and keys will be replaced with drops like bombs & cards
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Nuh Uh!
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Entering a new room has a 50% of granting a random passive item for the rest of the room
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Modeling Clay
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Clearing a room has a chance to spawn a friendly Bony
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Polished Bone
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Grants a bone heart at the start of every floor
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Hollow Heart
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Contributes to Guppy transformation
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Kid's Drawing
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Clearing a room has a 33% chance to open a red room
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Crystal Key
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50% for items that cost hearts to cost money
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Keeper's Bargain
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Teleports Isaac to random room when picking up a coin
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Cursed Penny
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Can be exhanged for a devil item, once used the trinket will vanish
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Your Soul
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+10% devil/angel chance, prevents Krampus from spawning in devil deals
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Number Magnet
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Unlocks a passageway to blue womb, can be used with Pandora's box
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Strange Key
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Spawns a Sumptorium clot
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Lil Clot
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Spawns a chest after the challenge room and an extra item from the boss trap room
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Temporary Tattoo
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Isaac has a 50% of exploding after taking damage
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Swallowed M80
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Familiars are now controlled by Isaac's inputs
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RC Remote
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Spawns a familiar that mimics Isaac's inputs but dies in one hit and spawns at the next floor
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Found Soul
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When Isaac uses an active item, a secondary random active item will trigger along with it
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Expansion Pack
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Spawns 5 wisps after entering an angel room
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Beth's Essense
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Entering a room has a 50% to duplicate one of Isaac's familiar
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The Twins
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Allows black markets and shops to sell items from the baby shop pool
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Adoption Papers
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Grants a chance for a 7 Seals locust to spawn when an enemy is killed
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Cricket Leg
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Spawns an Abyss locust with a 1.5x damage multiplier
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Apollyon's Best Friend
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50% to add a blind item to treasure rooms
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Broken Glasses
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Upon entering a room, enemies have a 20% to be petrified and frozen when killed
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Ice Cube
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Grants a shield for 1 second after killing an enemy
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Sigil of Baphomet
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