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Pharm Revision
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Last updated: October 29, 2024
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| First submitted | October 29, 2024 |
| Times taken | 19 |
| Average score | 13.3% | Report this quiz | Report |
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1. What is the mechanism of action for Disulfiram?
Inhibits aldehyde dehydrogenase
Blocks opioid receptors
Reduces cravings
Enhances excitatory neurotransmitters
2. What is the main concern with drugs in Category D?
Lack of studies in animals
Evidence of reversible effects
Potential for foetal damage
Inadequate information on human risks
3. What is the mechanism of action of Dexamethasone?
Block NK1 receptors
Inhibit H2 receptors
Inhibit prostaglandin synthesis
Stimulate appetite
4. Which diuretic is known to cause hyperkalemia?
Hydrochlorothiazide
Amiloride
Indapamide
Furosemide
5. What type of drug is Hyoscine Hydrobromide?
H2 receptor antagonist
Antimuscarinic
D2 receptor antagonist
5HT-3 antagonist
6. What does "down-scheduling" refer to?
Increasing restrictions on a drug
Banning a drug entirely
Adding a drug to the controlled substance list
Reducing the classification level of a drug
7. What is a side effect of Thiazide diuretics?
Oedema
Hypertension
Hypoglycemia
Hypokalemia
8. What is the primary action of Metoclopramide?
Reduce fluid retention
Increase gastrointestinal motility
Inhibit serotonin receptors
Block H1 receptors
9. What is the main side effect of corticosteroids like Prednisolone in IBD treatment?
Fluid retention
Weight loss
Nausea
Constipation
10. Which insulin type is considered "long-acting"?
Isophane
Glargine
Neutral
Asparat
11. What is the primary action of SGLT2 inhibitors?
Stimulate insulin secretion
Inhibit renal glucose reabsorption
Decrease hepatic glucose production
Increase glucose uptake
12. What is the purpose of drug scheduling?
To classify medicines for regulatory control
To enhance marketing strategies
To evaluate therapeutic effects
To categorise drugs by efficacy
13. Which drug is commonly used for ascites management?
Propranolol
Lactulose
Dexamethasone
Spironolactone
14. What is the main action of 5HT-3 antagonists like Dolasetron?
Inhibit serotonin action in the CTZ
Increase gastrointestinal motility
Enhance appetite
Block dopamine receptors
15. What adverse effect is associated with SGLT2 inhibitors?
Hypoglycemia
Constipation
Polyuria
Weight gain
16. What is the main mechanism of action of H2 receptor antagonists?
Neutralize gastric acid
Block dopamine receptors
Block histamine on parietal cells
Inhibit proton pumps
17. Which medication is a D2 receptor antagonist?
Fosaprepitant
Hyoscine
Ondansetron
Domperidone
18. What does Category B1 imply about a drug?
No evidence of foetal damage in animal studies
Insufficient human studies
Proven teratogenic effects in humans
Harmful effects shown in animals
19. What effect does metformin primarily have on the liver?
Increase insulin sensitivity
Increase glucose production
Decrease lipolysis
Decrease glucose production
20. What is a significant limitation of animal studies in assessing drug safety for humans?
They are more reliable than human studies
They provide clear human context
They always show direct human risks
They are often inconclusive
21. What is the primary role of antimuscarinics in nausea treatment?
Block acetylcholine
Increase motility
Block serotonin
Enhance dopamine effects
22. What is a potential side effect of stimulant laxatives?
Abdominal cramps
Fluid retention
Intestinal obstruction
Nausea
23. Which laxative should not be used in children?
Saline laxatives
Bulk-forming laxatives
Stool-softening laxatives
Stimulant laxatives
24. What is the mechanism of action of Furosemide?
Inhibit Na+/K+/2A-� symporter
Retain fluid osmotically
Inhibit sodium/chloride co-transporter
Block aldosterone
25. Which pregnancy category should never be used during pregnancy?
Category X
Category A
Category B
Category D
26. Which of the following is a PPI?
Calcium Carbonate
Omeprazole
Famotidine
Docusate
27. Which drug is an example of a bulk-forming laxative?
Ispaghula
Bisacodyl
Lactulose
Docusate
28. Which drug is an NK1 antagonist?
Dexamethasone
Aprepitant
Metoclopramide
Hyoscine
29. What is the action of bulk-forming laxatives like psyllium?
Irritate intestinal mucosa
Absorb water and stimulate peristalsis
Retain fluid osmotically
Soften the stool
30. Which type of insulin is classified as short-acting?
Glargine
Neutral
Asparate
Isophane
31. When prescribing medication during pregnancy, which practice point is crucial?
Prescribe without concern for fetal risk
Only prescribe if benefits outweigh risks
Recommend any drug with known safety
Use only new drugs
32. Which of the following categories is NOT a pregnancy category?
S
A
D
C
33. What is a common adverse effect of antacids containing magnesium?
Nausea
Constipation
Diarrhea
Abdominal pain
34. Which laxative should be avoided in patients with intestinal obstruction?
Lactulose
Psyllium
Docusate
Glycerol
35. What is a common systemic condition caused by corticosteroids used in IBD treatment?
Increased appetite
Hypertension
Infertility
Cushing's syndrome
36. Which laxative works by irritating the intestinal mucosa?
Docusate
Bisacodyl
Psyllium
Glycerol
37. Which medication is typically used for the PREVENTION of varices?
Acamprosate
Propranolol
Naltrexone
Terlipressin
38. What limitation is associated with the alphabetical hierarchy of pregnancy categories?
It implies a direct correlation with human risk
It accurately reflects risk levels
It considers drug dosage
It ignores clinical context
39. What is the mechanism of action of sulfonylureas?
Slow gastric emptying
Inhibit glucose reabsorption
Decrease hepatic glucose production
Increase insulin release from beta cells
40. What class does loperamide belong to?
Osmotic laxatives
Antidiarrhoeals
Stimulant laxatives
Antimuscarinics
41. Which drug is a TNF-a antagonist?
Azathioprine
Infliximab
Mesalazine
Budesonide
42. What is the primary action of Metformin?
Inhibit glucose reabsorption
Increase glucose uptake and decrease hepatic production
Increase insulin secretion
Block DPP-4 enzymes
43. Which pregnancy category indicates that a drug has been taken by a large number of pregnant women without an increase in malformations?
Category X
Category A
Category C
Category B
44. What side effect is associated with corticosteroids like Dexamethasone?
Fluid retention
Increased motility
Nausea
Constipation
45. What is the primary function of glucocorticoids in IBD treatment?
Promote healing
Block TNF-a
Inhibit inflammatory mediators
Increase inflammation
46. What should Naltrexone not be used in combination with?
Alcohol
Acamprosate
Disulfiram
Liver impairment
47. What is the effect of potassium-sparing diuretics?
Increase potassium loss
Cause sodium loss without potassium loss
Reduce sodium loss
Cause fluid retention
48. What defines a "Pharmacy Medicine"?
Safe to use but may need pharmacist advice
Requires medical supervision
Available only in hospitals
Requires a prescription
49. Triple therapy for H. pylori treatment typically includes which components?
H2 blocker + Metronidazole and Amoxicillin
Antacid + PPI + Amoxicillin
Lactulose + Clarithromycin + PPI/Antacid
PPI + 2x Amoxicillin, Clarithromycin, or Metronidazole
50. What is a potential adverse effect of using Azathioprine?
Increased inflammation
Weight gain
Hypertension
Thrombocytopenia
51. Which class of drugs does Ondansetron belong to?
Antimuscarinics
Corticosteroids
D2 receptor antagonists
5HT-3 antagonists
52. Which class of drugs includes Semaglutide?
Sulfonylureas
SGLT2 inhibitors
GLP-1 agonists
DPP-4 inhibitors
53. Which drug is often prescribed to manage ascites?
Spironolactone
Furosemide
Acamprosate
Propranolol
54. What is the primary role of antihistamines in treating nausea?
Enhance gastric motility
Block H1 receptors in the VC
Block acetylcholine in the VC
Block serotonin receptors in the VC
55. What is the primary action of 5-ASA drugs?
Anti-inflammatory effects
Antimicrobial effects
Analgesic effects
Immunosuppressive effects
56. Which medication is used for variceal TREATMENT?
Spironolactone
Lactulose
Terlipressin with Octreotide
Propranolol
57. Which medication can cause myelosuppression, hepatotoxicity and pulmonary toxicity, and is used in IBD?
Mesalazine
Methotrexate
Budesonide
Vedoluzimab
58. Which of the following is true about "Prescription Only Medicine"?
Can be sold without supervision
Requires a prescription for supply
Available over the counter
Is unscheduled medication
59. What kind of drug is Famotidine?
H2 receptor antagonist
Laxative
PPI
Antacid
60. Which class of diabetes medications can cause pancreatitis?
GLP-1 agonists
Sulfonylureas
DPP-4 inhibitors
SGLT2 inhibitors
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