Guess the Disease by Organ Manifestations

Guess the systemic disease that causes each of the following multi-organ manifestations.

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Last updated: December 17, 2024

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Hint	Answer
Polyarthritis, glomerulonephritis, pleuritis, malar rash	Systemic Lupus Erythematosus
Restrictive lung disease, restrictive cardiomyopathy, erythema nodosum	Sarcoidosis
Megaloblastic anemia, subacute combined degeneration of spinal cord	Vitamin B12 Deficiency
Bloody diarrhea, pyoderma gangrenosum, risk of colon cancer	Ulcerative Colitis
Nephrotic syndrome, cataracts, peripheral (axonal) polyneuropathy	Diabetes Mellitus

Hint	Answer
Aortic aneurysms, tabes dorsalis, Argyll Robertson pupils	Syphilis
Swimmer's itch, portal hypertension, pulmonary hypertension	Schistosomiasis
Bronchiectasis, chronic pancreatitis, constipation	Cystic Fibrosis
Hemolytic anemia, bone pain, asplenia	Sickle Cell Disease
Bone lytic lesions, anemia, susceptibility to infections, nephrolithiasis	Multiple Myeloma

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