NFL Players With 250+ Rushing Yards in a Game

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ncg1294
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Last updated: August 19, 2025
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First submittedAugust 19, 2025
Times taken32
Average score56.3%
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MIN - 296
Adrian Peterson
BAL - 295
Jamal Lewis
CLE - 286
Jerome Harrison
CIN - 278
Corey Dillon
CHI - 275
Walter Payton
BUF - 273
OJ Simpson
SEA - 266
Shaun Alexander
KC - 259
Jamaal Charles
PHI - 255
Saquon Barkley
IND - 253
Jonathan Taylor
DAL - 253
Demarco Murray
TB - 251
Doug Martin
DEN - 251
Mike Anderson
TEN - 250
Derrick Henry
BUF - 250
OJ Simpson
NY(Yankees) - 250
Spec Sanders
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