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15 Deadliest Epidemics/Pandemics in History

Guess each of the top 15 deadliest viruses of all time. Sources: Wikipedia, WHO https://en.wikipedia.org/wiki/List_of_epidemics_and_pandemics https://data.who.int/dashboards/covid19/deaths
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carsonThaBest
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Last updated: September 17, 2025
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First submittedSeptember 16, 2025
Times taken32
Average score26.7%
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Death Toll
Answer
#1. 17 - 100m
Spanish Flu
#2. 15 - 100m
Plague of Justinian
#3. 44m
HIV / AIDS pandemic
#4. 25 - 50m
Black Death
#5. 12 - 15m
Third Plague pandemic
#6. 5 - 15m
Cocoliztli epidemic (1545)
#7. 5 - 10m
Antonine Plague
#8. 5 - 8m
Aztec smallpox epidemic
#9. 7.1m
COVID-19 pandemic
#10. 1 - 4m
Asian Flu
#11. 1 - 4 m
Hong Kong Flu
#12. 2 - 3m
Russian typhus epidemic
#13. 2 - 2.5m
Cocoliztli epidemic (1576)
#14. 2m
Persian Plague
#15. 2m
Tenpyō Epidemic
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3 Comments
+1
Level 74
Sep 17, 2025
These aren't the deadliest viruses. These are the deadliest pandemics. For example, Black Death was a pandemic of a bacterium rather than a virus.
+1
Level 46
Sep 17, 2025
will change. thanks for pointing that out :)
+1
Level 74
Sep 18, 2025
Thank you for fixing the quiz!