MODA Cardiovascular and Renal Pharmacology Human Specific - Statistics

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General Stats

This quiz has been taken 4 times
The average score is 13 of 36

Answer Stats

Hint		Answer	% Correct
Anti-hypertensives	Diuretic	Furosemide	100%
Anti-dysrhythmics	Gi coupled -> increased K-ATP	Adenosine	67%
	False Transmitter, a2 agonist	aMethylDOPA	33%
Reperfusion Injury	Ischaemia creates ROS and	AMP	33%
Atherosclerosis	HMG-CoA Reductase inhibitorimpairs cholesterol synth ↑LDL uptake in liver	Arvostatin	33%
	beta blocker	Atenolol	33%
	beta antagonist	atenolol	33%
	Inhibits citrate production (needed +CoA to make cholesteol)	Bempedoic Acid	33%
	Fibrate - ↑lipoprotein lipase to release TAGs from VLDL to be absorbed by muscles	Bezafibrate	33%
	Cleaved twice to release a ___ type TF	bHLH	33%
	SCAP are	chaperones	33%
	Bile reabsorption inhibitor	Cholestyramine	33%
	a2 antagonist (Gi --> ↓NT Release)	Clonidine	33%
	Non-collateral vasodilator (diverts blood way from ischaemic region)	Dipyridamole	33%
	PCSK9 inhibitorPrevents recyling of LDL Familial Hypercholesterolaemia is LDLR mutation	Evolocumab	33%
	Inhibits intestinal cholesterol uptake (enterogepatic recirculation)	Ezetimibe	33%
	reduces hypertriglyceridaemia cia arachidonic acid replacement	fish oil	33%
	Sulphonylurea	Glibenclamide	33%
Angina	Collateral VasodilatorLiver converts to mononitrate (induces NO production)	Glyceryl trinitrate	33%
	Leaves ER to	Golgi	33%
	PCSK9 inhibitor (siRNA)	Inclisiran	33%
SREBP/SCAP Pathway	on what gene	INSIG	33%
	Funny current blocker (via HCN)	Ivabradine	33%
	which opens	K-ATP	33%
	Potassium Channel OpenerOpens K-ATP Hirsutism Severe Refractory Hypertension	Minoxidil	33%
	Imidazoline Receptor AgonistI1R is central GPCR -> ↑DAG + ArachAcid	Moxonidine	33%
	Which opens ____ in the mitochondria (close in ischaemia to prevent damage)	MPTP	33%
	Treat with ATP preservation drug or by opening K-ATP channels	Nicorandil	33%
	Stops liver TAG production and VLDL secretion + anticoagulative	nicotinic acid	33%
Reverse Cholesterol Transport Pathway	PPAR AgonistPPAR -> ↑Liver X Receptors -> ↑ABCA1 ->↑HDL	Pioglitazone	33%
	AMP leads to activation of	PKC	33%
	ACE Inhibitor	Ramipril	33%
	Late Na Current blocker, ↓NCX -> ↓Ca overload -> relaxation not impaired	Ranolazine	33%
	also treat with bypass or	stents	33%
	Calcium Blocker	Verapamil	33%
	calcium blocker	verapamil	33%

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