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Clue
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Drug
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CNS stimulant, indirectly acting sympathomimetic (IAS)
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amphetamines
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peptide hormone produced by beta cells in pancreas
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insulin
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Loop diuretic, inhibits NKCC2 in thick ascending limb of loop of Henle
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furosemide
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non-selective beta agonist
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isoprenaline
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blocks voltage-gated sodium channels, used as local anaesthetic or class I antidysrhythmic
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lidocaine
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predominantly beta-1 adrenergic agonist
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dobutamine
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prevents vesicular release of ACh, causing paralysis of muscles
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botulinum toxin
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competitive inverse agonist of muscarinic cholinergic receptors, non-selective
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atropine
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thiazide diuretic, inhibits sodium reabsorption at beginning of DCT
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bendroflumethiazide
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endogenous catecholamine, favours beta adrenergic receptors
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adrenaline
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potassium-sparing diuretic, blocks eNaC in DCT
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amiloride
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class III antidysrhythmic agent, prolongs phase 3 of cardiac action potential
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amiodarone
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clinically used cardiac glycoside, inhibits sodium/potassium ATPase in myocardium
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digoxin
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selective beta-1 adrenergic antagonist
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atenolol
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osmotic diuretic
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mannitol
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reversible AChE inhibitor, used to improve muscle tone in myasthenia gravis
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neostigmine
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proton-pump inhibitor
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omeprazole
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cardiac glycoside not clinically used, historically used in poison arrows
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ouabain
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antibiotic, discovered by Fleming
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penicillin
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short-acting beta-2 agonist
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salbutamol
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non-depolarising blocking agent, competes for cholinergic receptors at motor end plates.
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vecuronium
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diuretic - carbonic anhydrase inhibitor
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Acetazolamide
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NSAID, COX inhibitor
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aspirin
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depolarising neuromuscular blocker, acting on nicotinic receptors
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suxamethonium
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L-type calcium channel blocker
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verapamil
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nicotinic cholinergic receptor antagonist
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tubocurarine
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H2 histamine receptor antagonist
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ranitidine
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potassium-sparing diuretic, aldosterone antagonist
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spironolactone
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binds to voltage-gated sodium channels, blocking passage of sodium ions, found in pufferfish
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tetrodotoxin
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non-selective beta adrenergic receptor blocker
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propranolol
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Class Ib antidysrhythmic, used in treatment of some forms of long QT syndrome
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mexiletine
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