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Synaptic plasticity references - Statistics
General Stats
- This quiz has been taken 12 times
- The average score is 9 of 34
Answer Stats
| Hint | Author | Year | Methods | % Correct |
|---|---|---|---|---|
| Spatial pre-training in another maze ameliorated effects of above experiment | Bannerman | 1995 | 100%
| |
| Application of DA can convert LTD to LTP or reverse LTD depending on timing | Brzosko | 2015 | Schaffer-collateral CA1 pathway | 100%
|
| Calcium transients increased significantly after LTP induction | Emptage | 2003 | Calcium transients as indicators of release probability | 100%
|
| 10ms delay in somatic current injections could incur LTD or LTP depending on pairing (post-pre or pre-post) | Markram | 1997 | Somatic current injection into bidirectionally connected cells | 100%
|
| NMDAR-dependent LTP is required for associative spatial memory acquisition | Morris | 1986 | Mice, NMDAR antagonists | 100%
|
| Specific cells fired maximally when mouse is in specific parts of the environment | O'Keefe | 1971 | 100%
| |
| Most SC-CA1 have coexpression of NMDAR and AMPAR | Racca | 2010 | Immunogold NMDAR/AMPAR labelling | 100%
|
| AMPARs seen redistributed to dendritic spine surfaces | Shi | 1999 | GluR-1-GFP, electron microscopy | 100%
|
| STDP in xenopus retinotectal synaptic circuit | Zhang | 1998 | 100%
| |
| NMDAR blocker prevented LTP | Collingridge | 1983 | AP-5 applied in SC-CA1 pathway (rats) | 0%
|
| STDP in converging inhibitory and excitatory inputs | D'amour | 2015 | IPSCs/ EPSCs paired with postsynaptic APs respectively | 0%
|
| When GluR1 AMPARs coexpressed with CaMKII, increased conductance | Derkrach | 1999 | Patch-clamp recordings | 0%
|
| PKC inhibitor expressed under Purkinje-specific promoter in transgenic mice--> attenuated LTD, VOR adaptation impaired | De Zeeuw | 1998 | 0%
| |
| Purkinje-specific PKG KO in mice led to inability to induce LTD and impaired VOR adaptation | Feil | 2003 | 0%
| |
| A peptide preventing AMPAR internalisation blocked LTD induction and led to deficits in object recognition in rats | Griffiths | 2008 | 0%
| |
| No change in LTP when TTX applied to soma and axon | Hardie | 2009 | Stratum radiatum | 0%
|
| Isolated NMDAR-only cells; found AMPAR-EPSCs after LTP induction | Isaac | 1995 | 0%
| |
| Atypic PKC inhibitor returned EPSP to baseline after LTP induction | Ling | 2005 | 0%
| |
| Activation of postsynaptic CaMKII sufficient to induce LTP | Lledo | 1995 | Postsynaptic injection of preactivated CaMKII monomers | 0%
|
| EGTA (calcium chelator) blocked LTP | Lynch | 1983 | 0%
| |
| Intracellular photolysis of calcium caging compound was enough to induce LTP | Malenka | 1988 | 0%
| |
| CaMKII not required for LTP maintenance | Malinow | 1989 | CaMKII inhibitor added after induction of LTP | 0%
|
| STDP in the pre-post pairing of place cells | Meha | 1997 | Mice trained to run unidirectionally, specific cells fired in sequence | 0%
|
| Dendritic spikes are required for LTP | Remy | 2007 | TTX applied to soma, dendritic spikes recorded in neurons displaying LTP | 0%
|
| GluA1 -/- mice have large reductions in measures of spatial and directional selectivity | Resnik | 2012 | Radial maze--> decreased peformance | 0%
|
| Transgenic mice models with AMPAR internalisation defects attenuated LTD, although normal basic motor functions and no impairment of VOR adaptation | Schonewille | 2011 | 0%
| |
| Selective destruction of climbing fibres abolished NO responses | Shibuki | 1991 | NO probe | 0%
|
| Inhibition of CaMKII prevents induction of LTP | Silva | 1992 | CaMKII inhibitory peptide, mice with loss-of-function CaMKII mutation | 0%
|
| Decreased performance in a Morris water maze when LTP could not be induced, due to hippocampus-selective GluN1 KO | Tsien | 1996 | 0%
| |
| STDP can influence sensory receptive field | Vislay-Meltzer | 2006 | Mapped receptive fields of xenopus tectal neurons, flashes of light on retina paired with injection of somatic current | 0%
|
| PKMzeta KO mice had normal LTP | Volk | 2013 | 0%
| |
| STDP in inhibitory GABAergic synapses | Woodin | 2008 | 0%
| |
| Attenuated LTD by perfusing Purkinje cells with peptides interfering with PICK1/GluR interactions | Xia | 2000 | 0%
| |
| LTP increases transmitter release | Zakharenko | 2003 | FM1-43 dye (becomes fluorescent when integrated with membrane phospholipids | 0%
|
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