Wiring up the Brain references - Statistics

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This quiz has been taken 9 times
The average score is 6 of 26

Answer Stats

Hint	Author	Year	Methods	% Correct
Deep-to-superficial migration of radial glial cells	Angevine	1961	3[H]-thymidine injected at progressive stages during pregnancy (mice)- labelled progressively more superficial layers	100%
Tbr2 mutations in humans cause microcephaly, polymicrogyria and corpus callosum agenesis	Baala	2006		100%
Early Nkx2.1 removal led to gross deficit in cortical interneurons	Butt	2008		100%
CNTNAP2 KO mice have no gross abnormalities but ectopic neurons in corpus callosum; reduced number of cortical interneurons and mice showed autism-like behaviorus	Peñagarikana	2010	GAD1 staining (interneuron marker)	100%
Severed newt optic nerves, rotated eye 180degrees; recovered vision, RGCs made contact with original tectal targets	Sperry	1943		100%
Severed goldfish optic nerve, removed temporal retina; nasal axons regenerated to tectal targets	Sperry	1963		100%
CCPNs in SatB2 mutants are absent from corpus callosum, project through the internal capsule (CFuPN fate)	Alcamo	2008	Mice expressing LacZ from SatB2 locus	0%
Selective Tbr2 inactivation in mice caused selective deficits in SVZ progenitors	Arnold	2008	Sox1-Cre KO; in situ hybridisation	0%
Protease treatment abolished pattern by which temporal neurons usually avoid areas with caudal tectum membrane	Bahnhöffer	1987		0%
Retrovirus injections with eGFP to MGE progeny showed clustering of interneurons in cortex	Brown	2011		0%
Fezf2 over expression altered CCPN projection patterns to more closely resemble CFuPN patterns	Chen	2008		0%
Complimentary tectal, retinal gradients of ephrinA2; EphA3	Cheng	1995	In situ hybridisation, chicks	0%
Netrin1/DCC double KO mice have optic nerve hypoplasia	Deiner	1997		0%
Mutated reelin (Reeler mice) have inverted cortices	Falconer	1951		0%
Neurons turn away after making filopodial contact with semaphoring III beads	Fan	1995		0%
Cux2 is selectively expressed in upper cortical layers, but is seen in the cells of the VZ in mice at the earliest stage of neurogenesis (E14.5)	Franco	2012	In situ hybridisation	0%
EphA5 -/- mice; temporal RGCs were labelled in the caudal SC (only nasal in WT)	Frisen	1995	anterograde/retrograde staining	0%
Neurite outgrowth increased in laminin, fibronectin compared with collagen IV alone	Gundersen	1987	Chick DRG neurons cultured in these media; stripes of laminin	0%
All axons grew towards NGF source, sensitive to extremely low concentration	Gundersen	1979		0%
Selective Pals1 KO led to premature withdrawal of radial glia from cell cycle and severe cortical malformation	Kim	2010		0%
Clonally related interneurons found in cortical and subcortical areas separated by long distances	Mayer	2015	Retrovirus expressing unique DNA barcodes as label	0%
Transplant of labelled progenitor cells from E31 ferrets which normally form layer V/VI to proliferative zone of newborn ferrets where they would normally form layer II/III; saw 50:50 distribution	McConnell	1988		0%
Intermediate progenitors derive from radial glia, produce neurons	Noctor	2004	GFP labelling	0%
As above but with fluorescent markers	Paves	1997		0%
CPN migration is nearly all radial	Tan	1995	Female mice homozygous for LacZ on X chromosome; random X inactivation- beta galactosidase staining showed radial stripes	0%
Decreased density of GAD67 (interneuron marker) seen in schizophrenia	Volk	2000	In situ hybridisation of tissue sections from schizophrenia patients	0%

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