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A to Z: Infectious Diseases

Name the infectious disease that corresponds to the hint for each letter of the alphabet.
There are no commonly known infectious diseases beginning with J, U, or X
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Wallnutshire
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Last updated: September 19, 2021
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First submittedMay 22, 2016
Times taken2,966
Average score60.9%
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Letter
Hint
Answer
A
Immunodeficiency caused by HIV
AIDS
B
Killed up to 60% of Europe's population in the 14th century
Bubonic plague
C
Spread through contaminated water, results in severe diarrhoea and vomiting
Cholera
D
Mosquito-borne tropical disease with a characteristic skin rash
Dengue fever
E
Viral haemorrhagic disease spread through body fluids
Ebola
F
Colloquial name for the respiratory disease caused by influenza viruses
Flu
G
Relatively common bacterial STI
Gonorrhoea
H
Inflammation of the liver, caused by viruses named A to E
Hepatitis
I
Illness caused by Epstein-Barr virus, also known as glandular fever
Infectious mononucleosis
K
Prion disease endemic to Papua New Guinea
Kuru
L
Bacterial disease spread by infected ticks
Lyme disease
M
Mosquito-borne parasitic disease, originally treated with quinine
Malaria
N
Virus also known as the 'winter vomiting bug', named after Norwalk, Ohio
Norovirus
O
Infection of the middle ear, caused by a variety of infectious agents
Otitis media
P
Nearly-eradicated viral disease which can cause paralysis
Poliomyelitis
Q
Rare bacterial disease spread by domestic animals
Q fever
R
Viral disease historically known as 'hydrophobia'
Rabies
S
Viral disease declared eradicated in 1979 by the WHO
Smallpox
T
Bacterial disease that causes muscle spasms, sometimes known as 'lockjaw'
Tetanus
V
Fungal disease endemic to the southwestern United States
Valley fever
W
Spread by a virus named for an African river
West Nile fever
Y
Mosquito-borne viral tropical disease which can cause jaundice
Yellow fever
Z
Tropical viral disease that can cause microcephaly in newborn babies
Zika virus disease
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5 Comments
+2
Level 93
Apr 23, 2021
More-forgivable spelling on a few of these would be helpful. Perhaps the C, D, G & H answers?
+1
Level 78
Apr 24, 2021
I've added a few more spellings for those answers so it's a bit fairer. Thanks for the feedback!
+2
Level 75
Apr 23, 2021
Fantastic quiz! Learned a lot from it. Deserves more takes. Nominated :)
+1
Level 78
Apr 24, 2021
Thank you! Glad you enjoyed it.
+2
Level 55
May 23, 2025
This quiz is amazing. Rarest guess: Kuru. Knew it from Papua New Guinea cannibal tribes who were famous for catching this disease.