The English language is full of spelling and pronounciation irregularities. Use the clues to get the constituent words, which will show you how to pronounce the letters. Then sound out the strangely spelled word!
For example: Gh as in "tough", o as in "women", ti as in "nation"
Ghoti --> Fish
Made using this Wikipedia page: https://en.wikipedia.org/wiki/English_orthography
cough (off)
tough (uff)
dough (oh)
through (oo)
thought (aw)
bough (ow)
hiccough (up)
lough (ock)