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1.The Black Death pandemic killed 50-60% of Europe's population, about 50 million people.
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The Black Death pandemic ravaged Europe. There is not enough data available for an estimate of the worldwide death count.
2.The Black Death was an outbreak of plague.
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The Black Death was the first, and worst, six years of a recurring plague outbreak in Europe. Waves continued until the 1690s.
3.People typically catch plague from exposure to rat droppings.
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The primary vector of infection for plague is flea bites, fleas who often came into contact with humans because of rats.
4.The bubonic plague is caused by a protozoan parasite.
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The bubonic plague is caused by the bacterium Yersinia pestis.
5.Over 15 million people died during a major bubonic plague outbreak in India in the early 1900s.
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The third plague pandemic killed over 15 million in India, and more than 200 people still died per year up to the 1960s.
6.Viral epidemics have been far deadlier than bacterial epidemics since 1900.
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While cholera killed over 900,000 between 1961-2021, the vast majority of contagious disease deaths in the past 100 years have been viral, including HIV/AIDS, flu, and COVID.
7.Around 90% of the indigenous population of the Americas died from 1492-1600, largely as a result of the mass epidemic of European diseases like smallpox.
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The Columbian Exchange introduced smallpox, cholera, measles, diphtheria, flu, typhoid fever, and bubonic plague to the Americas.
8.More people have died from the HIV/AIDS epidemic than the COVID-19 pandemic.
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An estimated 33 million people have died from HIV/AIDS. Upwards of 27 million people died from COVID-19.
9.The Spanish flu killed an enormous amount of people, but never re-emerged after its lethal second wave.
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There were further waves of the Spanish flu, but the lethality of the disease dropped on subsequent waves. The current seasonal flu is probably a variant of Spanish Flu.
10.The Spanish Flu pandemic killed more people than any other pandemic in history.
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It is estimated that the Spanish Flue killed 50-100 million people in just 18 months.
11.Healthy young adults had a low mortality rate during the Spanish Flu epidemic.
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Young adults with good immune systems were most likely to die; they likely experienced "cytokine storms". Cytokines are the immune system's method of dealing with unknown bodily invaders. If the body overreacts, cytokines can destroy a person's own tissues.
12.The Spanish Flu originated in Spain.
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Spain was neutral during World War I, so they were the first country to allow media coverage of the illness. International media then called it Spanish flu.
13.Cholera is a bacterial infestation of the small intestine, typically spread by unsafe water.
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Cholera is an infection of the intestines by the bacterium Vibrio cholerae.
14.Less than 100,000 people died of cholera between 1865 and 1947 because of the advent of handwashing, sanitation, and vaccination.
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More than 23 million people died of Cholera in India alone during this period.
15.A cordyceps fungus that takes control of the brain stem has infected over 100 million people worldwide as of 2024.
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This is only true in the video game series The Last of Us.