Foundation Block A - Statistics

General Stats
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  • The average score is 10 of 20
Answer Stats
Question Answer % Correct
Which skin layer contains dead cells? Corneal layer
100%
What does side scatter measure in flow cytometry? Cytoplasmic complexity
100%
What activity does the sympathetic nervous system promote? Diverts blood to skeletal muscles
100%
Why are haemotoxylin and eosin used together? Haem = basic, eosin = acidic so bind to most substances
100%
Which immunoglobulin would you find in saliva? IgA
100%
Which is not a part of hair follicle? Malanosomes
100%
High respiratory rate may be a response to which problem? Acidosis
0%
What does adenylate cyclase do? Activates protein kinase A
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What do Ga type GPCR activate? Adenylate cyclase
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In spermatogenesis, where do primary spermatocytes come? After mitosis of simpler cells, before meiosis I
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What is a plasma blast? Antibody producing matured B cell
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Which is a domain of epithelial cells with specialised surface receptors? Apial
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What is ultrasound bad at viewing? Areas of behind air
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Which is not a part of connective tissue? Basal membrane
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Which cells may be able to recognise an epitope? B cells
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Where is immunoglobulin IgD only found? Bone marrow
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Where do cranial nerves originate? Brain
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Which root value would you not find in a sympathetic nerve? C5
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Give root values for brachial plexus C5 to T1
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Which muscle type is long lived and hard to replace? Cardiac
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What markers do helper T cells always have? CD45, CD3, CD4
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Which plexus has root value range between C1 and C4? Cervical
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Which comes first in ossification Chondrocytes expand and calcify cartilage
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What is most risky to patient? CT scans
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Which of the following in correct? Cystic fibrosis is recessive because it is not haploinsufficient
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What is the region of skin supplied by given nerve known as? Dermatome
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Which is not a property of pseudo-stratified columnar epithelial tissue? Different lengths
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What activates intracellular kinase domains on tyrosine kinase receptors? Dimerisation with another TKR upon ligand binding to extracellular domain
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What does red pulp of spleen do? Disposes of old red blood cells and platelets
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Which is an example of epigenetic gene regulation? DNA methylation
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Structural features of DNA which help high fidelity replication include... Double stranded template for easy checking
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What powers secondary active transport? Downhill transport of another molecule
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Why do more specialised cells tend to proliferate less? Energy and nutrients reserved for function
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Which cell type would be responsible for killing parasites? Eosinophil
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Which cell type has longest lifespan? Erythrocyte
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Heteroplasmy... explains why some children don't inherit mitochondrial diseases from their mother
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How does taqman PCR allow continual monitoring? Fluorescence of hybridised DNA sequence
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Are the BRCA genes dominant or recessive genetically and phenotypically? Genetically dominant, phenotypically recessive
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Where does affinity maturation mostly occur? Germinal centre
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Which is an adaptive immune cell responsible for majority of cytokine production? Helper T cell
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In adulthood, which bones no longer contain haematopoietic bone marrow? Humorous
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Which immunoglobulin is most prevalent in initial immune response? IgM
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Which of these might cause acidosis? Impaired lung function
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Which ligand might be detected by a tyrosine kinase receptor? Insulin
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Where are spinal nerve roots? Intervertebral foramen
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Which is incorrect about the possible effect of a mutation in 3' UTR on gene expression? It could increase
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What do DNA ligases do? Join adjacent Ozaki fragments in RNA processing
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Which system is most likely to be responsible for the bystander effect? Juxtacrine
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Which cell is not found in blood brain barrier? Langerhans cells
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Where does haematopoiesis occur mostly after first few weeks gestation? Liver
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Describe structure of para-sympathetic nerve. Long pre and short post ganglion nerve
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What does increased RAS activity correct? Low blood pressure
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Which is not part of positive feedback loop that causes hyperthermia? Lower respiratory rate
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Which is part of central nervous system Medulla
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Which specialised skin cell helps the skin to be protective? Melanocytes
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What balance is regulated by ATPase in cellular homeostasis? Membrane potential
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Which cells act as rudimentary touch receptors? Merkel cells
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A macrophage is a resident version of which cell type? Monocyte
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Which imaging technique is best for watery substances? MR scans
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What is the precursor to most phagocytic cells? Myoblast
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What can a myeloid progenitor not become? Natural killer cell
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What is different about necrosis and apoptosis Necrosis causes inflammatory response
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What makes proteoglycans good cushions in connective tissues Negatively charged saccharide chains repel to form spongey matrix
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Which cells produce bone? Osteocytes
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What process tests for CpG methylation PCR with bisulfites added to DNA
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Which activity is independent from brain? Peristalsis
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What is benefit of producing polar bodies in oogenesis? Preserves nutrients for other ovum
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Which is not a function of the endoplasmic reticulum Producing ribosomal RNA
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Which will haematoxylin not bind to? Protein
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Which statement is not true about pH balance regulation in a cell? Protons are taken up by cell from the blood
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What causes antibody diversity in blood cells? Random recombination
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What does RAS cascade not cause? Reduced thirst
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What does parasympathetic system increase? Saliva production
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What is cAMP? Secondary intracellular messenger
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What type of nerve emerges from dorsal root? Sensory
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What can NeXT gen DNA sequencing do that Sanger can't? Shows different alleles speperately
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Which epithelial tissue is found in small intestine? Simple columnar
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Which epithelial tissue is found in alveoli? Simple squamous
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Which muscle is not striated? Smooth
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Which type of connective tissue does cartilage come under? Specialised
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What would you find in vertebral foramen in spine? Spinal chord
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Which ligands will nuclear receptors respond to? Steroids
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What is the T in STR? Tandem
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What is different about dideoxy nucleotides? They can't polymerise
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What happens to chondrocytes during ossification? They swell, calcify cartilage then are suffocated by calcified cartilage
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What is STR profiling used for? To find characteristics associated with a gene
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Which disease causes hyperammonaemia Urea cycle disorder - OTC deficiency
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Which does not require active transport across membrane? Viruses
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What is a nerve plexus? When nerves join into a network with those above and below
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