pharmacokinetic equations

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Last updated: April 19, 2023

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First submitted	April 19, 2023
Times taken	29
Average score	60.0%
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Hint	Answer
Four hours after intravenous administration of a drug, a patient was found to have a drug plasma concentration of 60 μg/mL. Assuming the apparent volume of distribution is 10% of an average body weight of 90 kg, calculate the total amount of drug present in body fluids four hours after administration.	540 mg
What is the plasma concentration of a drug when 800 mg is given by IV bolus to a 75kg patient if her volume of distribution is 2.1L/kg.	5.080 mg/L
A single intravenous dose of 64 mg of diazepam was administered to a patient. A blood sample was drawn and it contained 68 µg/mL. Calculate the apparent volume of distribution for the drug.	0.94 L
A drug has an elimination rate constant of 0.845 hr-1. Its elimination half-life is:	0.82 hrs
What is the plasma concentration of a drug when 200 mg is given by IV bolus to a 65kg patient if her volume of distribution is 16 L/kg.	0.192 mg/L
A drug has an elimination rate constant of 0.296 hr-1. Its elimination half-life is:	2.34 hrs
Assuming complete absorption and an elimination half-life of 8 hours, how many mg of a drug will remain in the body 40 hours after administering a 500 mg dose?	15.625 mg
What is the plasma concentration of a drug when 800 mg is given by IV bolus to a 90kg patient if her volume of distribution is 25 L/kg.	0.355 mg/L
Calculate the elimination rate constant for a drug having an elimination half-life of 19 minutes.	2.19/hr
Assuming complete absorption and an elimination half-life of 8 hours, how many mg of a drug will remain in the body 42 hours after administering a 350 mg dose?	9.197 mg