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Microbiology Quiz #8

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DylanJay05
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Last updated: May 5, 2024
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First submittedMay 5, 2024
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Average score17.4%
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Lowest concentration of drug that kills pathogen
Minimal lethal concentration
Drug level at which drug becomes too toxic for patient (i.e., produces side effects)
Toxic dose
Ability of drug to kill or inhibit pathogen while damaging host as little as possible
Selective toxicity
Which inhibitor mimics peptide bond that is normally attacked by the enzyme?
Protease
Test where disks impregnated with specific drugs are placed on agar plates inoculated with test microbe
Disk Diffusion
Lowest concentration of drug that inhibits growth of pathogen
Minimal inhibitory concentration
What do β-lactams and vancomycin target?
Cell Wall
Antimicrobial agent which kills microbes
Cidal
Test which involves inoculating media containing different concentrations of drug
Dilution Susceptibility
Antimicrobial agent which limits growth of microbes
Static
Who accidentally discovered penicillin in 1928?
Alexander Fleming
Standardized method for disk diffusion test
Kirby-Bauer Method
Drug level required for clinical treatment
Therapeutic dose
What do linezolid, tetracyclines, macrolides, and aminoglycosides target?
Protein synthesis
Drugs effective against a limited number of different pathogens
Narrow Spectrum
Drugs effective against a wider range of different pathogens
Broad spectrum
Tests strips which contain a gradient of an antibiotic, convenient for use with anaerobic pathogens
ETest
Who originally discovered penicillin in 1896?
Ernest Duchesne
What do fluoroquinolones and rifamycin's target?
DNA/RNA synthesis
What do trimethoprim and sulphonamides target?
Folate synthesis
Ratio of toxic dose to therapeutic dose
Therapeutic index
What does daptomycin target?
Cell membrane
What does penicillin prevent bacteria from completing causing lysis?
Cell wall
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