Multiple Myeloma Quiz

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Last updated: December 30, 2023

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First submitted	December 30, 2023
Times taken	14
Average score	68.4%
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Hint	Answer
What is the acronym for remembering the clinical signs of multiple myeloma?	CRAABB
Give the clinical sign that each letter of the acronym stands for.	Calcium >2.8 / Hypercalcaemia
	Renal impairment
	Anaemia
	Amyloid
	Bone lesions
	Bone marrow plasma cells >10%
Which cytokines are involved in activating osteoclasts and causing them to mature in multiple myeloma?	IL-1B
	IL-6
	RANKL

Hint	Answer
What is the name of the light chain proteins found in the urine (and plasma) of MM patients?	Bence Jones proteins / paraproteins / m-proteins
List the three causes of renal failure in patients with MM.	Bence Jones proteins
	Calcium stones
	Amyloid
What test is used for diagnosing multiple myeloma?	Serum electrophoresis
What does the above test look for/detect?	Monoclonal bands (monoclonal paraprotein in the serum)
What serology test is used to determine the type of immunoglobulin affected in MM?	Immunofixation
Which immunoglobulins are most commonly affected in MM?	IgG and IgA
What other serology test can be used to aid in diagnosis?	Serum free light chain (FLC) analysis

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