| Hint | Answer | % Correct |
|---|---|---|
| What is the acronym for remembering the clinical signs of multiple myeloma? | CRAABB | 100%
|
| Give the clinical sign that each letter of the acronym stands for. | Calcium >2.8 / Hypercalcaemia | 88%
|
| IL-6 | 88%
| |
| What does the above test look for/detect? | Monoclonal bands (monoclonal paraprotein in the serum) | 88%
|
| Renal impairment | 88%
| |
| What test is used for diagnosing multiple myeloma? | Serum electrophoresis | 88%
|
| List the three causes of renal failure in patients with MM. | Bence Jones proteins | 75%
|
| What is the name of the light chain proteins found in the urine (and plasma) of MM patients? | Bence Jones proteins / paraproteins / m-proteins | 75%
|
| Amyloid | 63%
| |
| Amyloid | 63%
| |
| Anaemia | 63%
| |
| Which cytokines are involved in activating osteoclasts and causing them to mature in multiple myeloma? | IL-1B | 63%
|
| Bone lesions | 50%
| |
| Bone marrow plasma cells >10% | 50%
| |
| Calcium stones | 50%
| |
| What serology test is used to determine the type of immunoglobulin affected in MM? | Immunofixation | 50%
|
| What other serology test can be used to aid in diagnosis? | Serum free light chain (FLC) analysis | 50%
|
| RANKL | 38%
| |
| Which immunoglobulins are most commonly affected in MM? | IgG and IgA | 25%
|