Bacteria 5 (toxins)

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Last updated: April 3, 2019

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First submitted	April 3, 2019
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Average score	45.5%
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Hint

Answer

Pertussis toxin and which other ADP-ribosylate regulators of adenylate cyclase, leading to disturbance of CAMP levels,signalling and ion balance?

Cholera

Which toxin targets translation elongation factor 2, leading to arrest of protein synthesis?

Diptheria

What toxin is a glycosidase that depurinates 28S rRNA, blocking protein synthesis?

Shiga

What antibiotic resistant bacteria's toxin glucosylate small GTPases involved in signal transduction, disrupting actin cytoskeleton?

Clostridium difficile

What deamidase that targets host cell GTPases, disrupting cell signal transduction is produced by UPEC?

Cytotoxic Necrotizing Factor

What type of toxin are both tetanus and botulinum toxin?

Neurotoxin

What does the A-chain of tetanus cleave leading to the prevention of release of inhibitory neurotransmitter?

Synaptobrevin

What type of paralysis does botulinum toxin lead to?

Flaccid

What is the end result of over stimulation of T cells due to super antigens?

Cytokine storm

What bacteria producing superantigens leads to toxic shock syndrome?

Staph. aureus

What component of LPS also known as endotoxin triggers acute inflammation?

Lipid A

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