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key pharmacology equations - Statistics

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Hint Answer % Correct
p (fractional occupancy) = [d]/([d] + Kd)
100%
Kd = ([d][r])/[dr]
100%
half life in association assays = 0.693/Kobs
0%
half life in dissociation assays = 0.693/Koff
0%
half life (ADME) = (0.693*Vd)/clearance
0%
gaddum-schild: concentration ratio = 1 + [b]/Kb
0%
Cp = amount of drug/Vd
0%
rate of elimination = clearance*Cp
0%
rate of infusion = Css*clearance
0%
Css (average) = (dose*oral bioavailability)/(time between doses*clearance)
0%
cheng-prusoff: Ki = IC50/(1+[l]/Kd)
0%
Kon = (Kobs - Koff)/[l]
0%
henderson-hasselbalch for weak acids pH = pKa + log[A-]/[HA]
0%
henderson-hasselbalch for weak bases pH = pKa + log [HA]/A-]
0%
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