Synovial Fluid Cells

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yannnnn
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Last updated: April 15, 2026
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First submittedApril 15, 2026
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Average score16.7%
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Polymorphonuclear leukocyte
Neutrophil
Neutrophil with dark cytoplasmic granules containing immune complexes
RA cell
Macroscopically resemble polished rice Microscopically show collagen & fibrin
Rice bodies
Large mononuclear leukocyte, may be vacuolated
Macrophage
Neutrophil containing ingested "round body”
LE cell
Refractile intracellular & extracellular globules Stain with Sudan dyes
Fat droplets
Similar to macrophage, but may be multinucleated, resembling a mesothelial cell
Synovial lining cell
Inclusions within clusters of synovial cells
Hemosiderin
Large, multinucleated cells
Cartilage cells
Debris from metal & plastic joint prosthesis “Ground pepper” appearance
Ochronotic shards
Vacuolated macrophage with ingested neutrophils
Reiter cell
Mononuclear leukocyte
Lymphocytes
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