| Ranking | Player | Positions | Nationality | Matches | Goals (assists) | Periods | Clubs | % Correct |
|---|---|---|---|---|---|---|---|---|
| 12 | Chris Wondolowski | ST | 410 | 169 (41) | 2005-2021 | 100%
| ||
| 9 | Diego Chará | CM | 423 | 12 (23) | 2011-2025 | 100%
| ||
| 10 | Diego Fagúndez | LW | 422 | 79 (62) | 2011-2025 | 100%
| ||
| 4 | Kei Kamara | ST | 461 | 146 (50) | 2006-2013, 2015-2020, 2022-2025 | 100%
| ||
| 2 | Kyle Beckerman | DM | 496 | 41 (34) | 2000-2020 | 100%
| ||
| 1 | Nick Rimando | GK | 514 | 0 (3) | 2000-2019 | 100%
| ||
| 13 | Chad Marshall | CB | 409 | 27 (14) | 2004-2019 | 50%
| ||
| 5 | Darlington Nagbe | CM | 442 | 38 (34) | 2011-2025 | 50%
| ||
| 3 | Dax McCarty | CM | 488 | 22 (49) | 2006-2024 | 50%
| ||
| 14 | Drew Moor | CB | 409 | 28 (8) | 2005-2022 | 50%
| ||
| 6 | Jeff Larentowicz | DM | 434 | 42 (16) | 2005-2020 | 50%
| ||
| 8 | Sean Johnson | GK | 428 | 0 (1) | 2010-2025 | 50%
| ||
| 7 | Stefan Frei | GK | 430 | 0 (2) | 2009-2011, 2013-2025 | 50%
| ||
| 11 | Teal Bunbury | ST | 413 | 75 (32) | 2010-2025 | 50%
|