Cardiovascular and Renal Pharmacology - Statistics

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General Stats

This quiz has been taken 18 times
The average score is 9 of 44

Answer Stats

Hint		Answer	% Correct
Loop Diuretic	Blocks NKCC in TALHypokalaemia Venodilation Uric Acid Retention Ca + Mg Excretion	Furosemide	85%
Potassium Sparring Diuretic	Inhibits Aldosteronevia carenone salt AldR competition	Spironolactone	62%
Calcium Channel Blocker	Dihydropyridine	Amlodipine	38%
AT1R Inhibitor	Prevents Angiotensin 2 action	Losartan	38%
ACE inhibitor	↑Bradykinin (inflam+pain) so use AIIR inhib instead	Ramipril	38%
Factor Xa Inhibitor		Apixaban	31%
Calcium Channel Blocker	Benzothiazepine	Diltiazem	31%
Osmotic Diuretic	Treat Cerebral Oedema (no BBB crossing)	Mannitol	31%
Calcium Channel Blocker	Phenylalkylamine	Verapamil	31%
Thrombin Inhibitor	Prevents synth of Factors 2,7,9,10Interacts with food a lot	Warfarin	31%
Renin Inhibitor		Aliskiren	23%
Class II Dysrhythmic	beta1 adrenoceptor antagonist	Atenolol	23%
Thiazide Diuretic	Blocks Na-Cl Cotransport in DCTHypokalaemia Uric Acid retention Ca + Mg Excretion Increases blood glucose	Bendroflumethiazide	23%
SGLT Inhibitor	Lowers blood glucose as well	Dapagliflozin	23%
NCX Inhibitor	Cardiac Glycoside	Digoxin	23%
b1 AR Agonist	Increase CO but increases O2 demandUse antagonist to reduce adrenergic toxicity	Dobutamine	23%
Class Ic Dysrhythmic	Slow, no AP effects	Flecainide	23%
Thrombin Inhibitor	Activates antiThrombin IIICauses thrombocytopenia	Heparin	23%
Local Anaesthetic	Use dependence	Lidocaine	23%
Gp IIb/IIIa inhibitor		Abciximab	15%
Carbonic Anhydrase Inhibitor	vs Glaucoma + altitude sickness	Acetazolamide	15%
Potassium Sparring Diuretic	Inhibits ENaC in DCT	Amiloride	15%
Class III Dysrhythmic	Inhibits inwards Na + outwards Kprolongs AP and refractory period	Amiodarone	15%
Thrombin Inhibitor	Reduce HIT	Argatroban	15%
Local Anaesthetic	pKA 2.6 (99% unprotonated at normal pH)	Benzocaine	15%
Thrombin Inhibitor	Leech Saliva homologue	Bivalirudin	15%
ADP-Platelet Receptor Inhibitor	Ineffective vs homozygous CYP2C19 mutations	Clopidogrel	15%
Thrombin Inhibitor	Treat A-Fib, use prophylactically for surgery	Dabigatran	15%
Calcium Sensitiser	Increases binding to Troponin. Inhibits PDE	Levosimendan	15%
Class Ib Dysrhythmic	Fast, shortens AP	Lidocaine	15%
Activates Plasminogen Activator	From Streptomycin	Streptokinase	15%
Gp IIb/IIIa Inhibitor	Prevents Fibrin and vWF binding	Tirofiban	15%
Plasminogen Inhibitor		Tranexamic Acid	15%
Class IV Dysrythmic	L-Type calcium channel blocker	Verapamil	15%
Activates Plasminogen	TIssue plasminogen activator made from recombinant DNA	Altepase	8%
Slow release anti-clot	Plasminogen + anisoylated streptokinase	Anistreplase	8%
VGNaC Toxin	Prevents inactivation of NaC	Batrachotoxin	8%
Low Weight Heparin	Reduce HIT	Danaparoid	8%
NCX Inhibitor	Cardiac Glycoside	Ouabain	8%
Class Ia Dysrhythmic	Medium duration, lengthens AP	Quinidine	8%
K-ATP antagonist	ATP Analogue	Sulphonylurea	8%
Local Anaesthetic	pKA 8.5 (less effective at lower pH)	Tetracaine	8%
VGNaC Toxin	Binds Glu on S6 Domain IV	Tetrodotoxin	8%
Non-Diuretic Thiazide	Opens K-ATP for more InsulinVasodilator	Diazoxide	0%

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