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Pharmacology of Peripheral Neural Transmission
Important Drugs from Dr Taufiq Rahman's Lecture Series 22/23
Quiz by
yeahbutyou
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Last updated: May 15, 2023
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First submitted
May 15, 2023
Times taken
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Average score
66.0%
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Hint
Answer
Inhibit ChT
Rate limiting for ACh Synthesis
Hemicholinium
Inhibit VAChT
Vesamicol
Nn Agonist
Desensitise at high conc.
Nicotine
Nn Agonist
Quit smoking
Varenicline
Nn Anatagonist
Trimethaphan
Nn Antagonist
Hexamethonium
Depolarising Nm Antagonist
degraded by pseudoAChE
Phase I fasciculations
Phase II Desensitisation
Hyperkalaemia
Suxamethonium
Non-depolarising Nm Antagonist
Curare
Non-depolarising Nm Antagonist
Aminosteroid
Rocuronium
Non-depolarising Nm Antagonist
Benzylisoquinolinium
Atracurium
mAChR Agonist
Stim Detrusor M3
Bethanechol
mAChR Agonist
Glaucoma, accomodation spasm
Pilocarpine
mAChR Antagonist
M2 in SAN
Atropine
mAChR Antagonist
M3 COPD
Ipatropium
mAChR Antagonist
M3 Incontinence
Solifenacin
AntiCholinesterase
Blocks CAS, diagnose Myasthenia
Edrophonium
AntiCholinesterase
Carbamylates Ser
Neostigmine
AntiCholineseterase
Phosphorylates Ser
Organophosphates
Treat Sarin
Pralidoxime
Inhibits VMAT2
Causes depression, antihypertensive
Reserpine
Competes for TOH
Treat Phaeochromocytoma
aMethylTyrosine
False Transmitter production
aMethylDOPA
Inhibits DDC
Peripheral only
Carbidopa
Block catecholamine release
Accumulates via NET/VMAT2
Guanethidine
Indirect Sympathomimetic
Cheese Effect
Tyramine
Hint
Answer
Indirect Sympathomimetic
Treat Narcolepsy
Dexamfetamine
Mixed Sympathomimetic
Bronchodilation + nasal vasoconstriction (Decongestant)
Ephedrine
Block NET
Cocaine
Block NET
Imipramine
Block ENT
Corticosteroids
COMT inhibitor
+ Carbidopa + aMethylDOPA vs Parkinsons
Entacapone
Non-selective AR Agonist
Anaphylaxis
Adrenaline
a AR Agonist
Xylometazoline
a AR Agonist
Noradrenaline
a1 AR Agonist
Nasal Decongestant
Phenylephrine
a2 AR Agonist
Hypotensive Agent via decrease NT Release
Clonidine
a2 AR Agonist
aMethylDOPA
b AR Agonist
Asthma but high HR
Isoprenaline
b1 AR Agonist
Cardiogenic Shock but causes dysrythmia
Dobutamine
b2 AR Agonist
Asthma
Salbutamol
b2 AR Agonist
COPD
Salmeterol
b3 AR Agonist
Relaxes Bladder
Mirabegron
a AR Antagonist
Hypotensive
Phenoxybenzamine
a1 AR Antagonist
↓ TPR, ↓ BP, incontinence
Prazosin
a1 AR Antagonist
Relaxes prostate ↓ hypertrophy
Tamulosin
a2 AR Antagonist
Yohimbine
b AR Antagonist
↓CO, but ↓ renin + ↓TPR
Propranolol
b1 AR Antagonist
↓CO
Atenolol
b1 AR Antagonist
↓CO + NO Release
Nebivolol
ATP Antagonist
Suramin
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