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Microbiology Quiz #8

Quiz by
DylanJay05
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Last updated: May 5, 2024
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First submittedMay 5, 2024
Times taken12
Average score17.4%
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Hint
Answer
What do fluoroquinolones and rifamycin's target?
DNA/RNA synthesis
Antimicrobial agent which kills microbes
Cidal
Lowest concentration of drug that kills pathogen
Minimal lethal concentration
Drug level required for clinical treatment
Therapeutic dose
Test which involves inoculating media containing different concentrations of drug
Dilution Susceptibility
What does penicillin prevent bacteria from completing causing lysis?
Cell wall
What do trimethoprim and sulphonamides target?
Folate synthesis
Test where disks impregnated with specific drugs are placed on agar plates inoculated with test microbe
Disk Diffusion
What do linezolid, tetracyclines, macrolides, and aminoglycosides target?
Protein synthesis
Which inhibitor mimics peptide bond that is normally attacked by the enzyme?
Protease
What does daptomycin target?
Cell membrane
Tests strips which contain a gradient of an antibiotic, convenient for use with anaerobic pathogens
ETest
Hint
Answer
Drugs effective against a limited number of different pathogens
Narrow Spectrum
Ability of drug to kill or inhibit pathogen while damaging host as little as possible
Selective toxicity
Drugs effective against a wider range of different pathogens
Broad spectrum
Drug level at which drug becomes too toxic for patient (i.e., produces side effects)
Toxic dose
What do β-lactams and vancomycin target?
Cell Wall
Standardized method for disk diffusion test
Kirby-Bauer Method
Who originally discovered penicillin in 1896?
Ernest Duchesne
Who accidentally discovered penicillin in 1928?
Alexander Fleming
Lowest concentration of drug that inhibits growth of pathogen
Minimal inhibitory concentration
Antimicrobial agent which limits growth of microbes
Static
Ratio of toxic dose to therapeutic dose
Therapeutic index
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