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Pharm Revision
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Last updated: October 29, 2024
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| First submitted | October 29, 2024 |
| Times taken | 19 |
| Average score | 13.3% | Report this quiz | Report |
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1. What is the mechanism of action for Disulfiram?
Blocks opioid receptors
Reduces cravings
Enhances excitatory neurotransmitters
Inhibits aldehyde dehydrogenase
2. What is the main concern with drugs in Category D?
Potential for foetal damage
Inadequate information on human risks
Evidence of reversible effects
Lack of studies in animals
3. What is the mechanism of action of Dexamethasone?
Stimulate appetite
Block NK1 receptors
Inhibit H2 receptors
Inhibit prostaglandin synthesis
4. Which diuretic is known to cause hyperkalemia?
Indapamide
Furosemide
Hydrochlorothiazide
Amiloride
5. What type of drug is Hyoscine Hydrobromide?
H2 receptor antagonist
D2 receptor antagonist
5HT-3 antagonist
Antimuscarinic
6. What does "down-scheduling" refer to?
Reducing the classification level of a drug
Banning a drug entirely
Adding a drug to the controlled substance list
Increasing restrictions on a drug
7. What is a side effect of Thiazide diuretics?
Hypertension
Oedema
Hypokalemia
Hypoglycemia
8. What is the primary action of Metoclopramide?
Increase gastrointestinal motility
Block H1 receptors
Inhibit serotonin receptors
Reduce fluid retention
9. What is the main side effect of corticosteroids like Prednisolone in IBD treatment?
Constipation
Nausea
Weight loss
Fluid retention
10. Which insulin type is considered "long-acting"?
Asparat
Glargine
Neutral
Isophane
11. What is the primary action of SGLT2 inhibitors?
Inhibit renal glucose reabsorption
Stimulate insulin secretion
Increase glucose uptake
Decrease hepatic glucose production
12. What is the purpose of drug scheduling?
To evaluate therapeutic effects
To enhance marketing strategies
To classify medicines for regulatory control
To categorise drugs by efficacy
13. Which drug is commonly used for ascites management?
Dexamethasone
Propranolol
Spironolactone
Lactulose
14. What is the main action of 5HT-3 antagonists like Dolasetron?
Block dopamine receptors
Inhibit serotonin action in the CTZ
Enhance appetite
Increase gastrointestinal motility
15. What adverse effect is associated with SGLT2 inhibitors?
Polyuria
Constipation
Weight gain
Hypoglycemia
16. What is the main mechanism of action of H2 receptor antagonists?
Block histamine on parietal cells
Inhibit proton pumps
Block dopamine receptors
Neutralize gastric acid
17. Which medication is a D2 receptor antagonist?
Fosaprepitant
Domperidone
Ondansetron
Hyoscine
18. What does Category B1 imply about a drug?
Insufficient human studies
Harmful effects shown in animals
No evidence of foetal damage in animal studies
Proven teratogenic effects in humans
19. What effect does metformin primarily have on the liver?
Increase insulin sensitivity
Increase glucose production
Decrease glucose production
Decrease lipolysis
20. What is a significant limitation of animal studies in assessing drug safety for humans?
They provide clear human context
They always show direct human risks
They are more reliable than human studies
They are often inconclusive
21. What is the primary role of antimuscarinics in nausea treatment?
Block acetylcholine
Block serotonin
Increase motility
Enhance dopamine effects
22. What is a potential side effect of stimulant laxatives?
Abdominal cramps
Fluid retention
Intestinal obstruction
Nausea
23. Which laxative should not be used in children?
Stimulant laxatives
Stool-softening laxatives
Bulk-forming laxatives
Saline laxatives
24. What is the mechanism of action of Furosemide?
Inhibit Na+/K+/2A-� symporter
Retain fluid osmotically
Inhibit sodium/chloride co-transporter
Block aldosterone
25. Which pregnancy category should never be used during pregnancy?
Category B
Category X
Category A
Category D
26. Which of the following is a PPI?
Omeprazole
Docusate
Calcium Carbonate
Famotidine
27. Which drug is an example of a bulk-forming laxative?
Ispaghula
Bisacodyl
Lactulose
Docusate
28. Which drug is an NK1 antagonist?
Hyoscine
Aprepitant
Dexamethasone
Metoclopramide
29. What is the action of bulk-forming laxatives like psyllium?
Absorb water and stimulate peristalsis
Irritate intestinal mucosa
Retain fluid osmotically
Soften the stool
30. Which type of insulin is classified as short-acting?
Isophane
Neutral
Asparate
Glargine
31. When prescribing medication during pregnancy, which practice point is crucial?
Use only new drugs
Only prescribe if benefits outweigh risks
Recommend any drug with known safety
Prescribe without concern for fetal risk
32. Which of the following categories is NOT a pregnancy category?
A
S
D
C
33. What is a common adverse effect of antacids containing magnesium?
Constipation
Nausea
Abdominal pain
Diarrhea
34. Which laxative should be avoided in patients with intestinal obstruction?
Glycerol
Docusate
Lactulose
Psyllium
35. What is a common systemic condition caused by corticosteroids used in IBD treatment?
Cushing's syndrome
Hypertension
Infertility
Increased appetite
36. Which laxative works by irritating the intestinal mucosa?
Bisacodyl
Docusate
Psyllium
Glycerol
37. Which medication is typically used for the PREVENTION of varices?
Naltrexone
Terlipressin
Acamprosate
Propranolol
38. What limitation is associated with the alphabetical hierarchy of pregnancy categories?
It implies a direct correlation with human risk
It considers drug dosage
It ignores clinical context
It accurately reflects risk levels
39. What is the mechanism of action of sulfonylureas?
Slow gastric emptying
Inhibit glucose reabsorption
Increase insulin release from beta cells
Decrease hepatic glucose production
40. What class does loperamide belong to?
Osmotic laxatives
Stimulant laxatives
Antidiarrhoeals
Antimuscarinics
41. Which drug is a TNF-a antagonist?
Mesalazine
Azathioprine
Infliximab
Budesonide
42. What is the primary action of Metformin?
Increase insulin secretion
Increase glucose uptake and decrease hepatic production
Inhibit glucose reabsorption
Block DPP-4 enzymes
43. Which pregnancy category indicates that a drug has been taken by a large number of pregnant women without an increase in malformations?
Category X
Category B
Category C
Category A
44. What side effect is associated with corticosteroids like Dexamethasone?
Increased motility
Nausea
Fluid retention
Constipation
45. What is the primary function of glucocorticoids in IBD treatment?
Promote healing
Inhibit inflammatory mediators
Increase inflammation
Block TNF-a
46. What should Naltrexone not be used in combination with?
Disulfiram
Liver impairment
Alcohol
Acamprosate
47. What is the effect of potassium-sparing diuretics?
Reduce sodium loss
Increase potassium loss
Cause sodium loss without potassium loss
Cause fluid retention
48. What defines a "Pharmacy Medicine"?
Safe to use but may need pharmacist advice
Requires a prescription
Available only in hospitals
Requires medical supervision
49. Triple therapy for H. pylori treatment typically includes which components?
H2 blocker + Metronidazole and Amoxicillin
Antacid + PPI + Amoxicillin
Lactulose + Clarithromycin + PPI/Antacid
PPI + 2x Amoxicillin, Clarithromycin, or Metronidazole
50. What is a potential adverse effect of using Azathioprine?
Increased inflammation
Thrombocytopenia
Hypertension
Weight gain
51. Which class of drugs does Ondansetron belong to?
Antimuscarinics
5HT-3 antagonists
D2 receptor antagonists
Corticosteroids
52. Which class of drugs includes Semaglutide?
GLP-1 agonists
Sulfonylureas
SGLT2 inhibitors
DPP-4 inhibitors
53. Which drug is often prescribed to manage ascites?
Acamprosate
Spironolactone
Furosemide
Propranolol
54. What is the primary role of antihistamines in treating nausea?
Block H1 receptors in the VC
Block serotonin receptors in the VC
Enhance gastric motility
Block acetylcholine in the VC
55. What is the primary action of 5-ASA drugs?
Anti-inflammatory effects
Analgesic effects
Immunosuppressive effects
Antimicrobial effects
56. Which medication is used for variceal TREATMENT?
Propranolol
Terlipressin with Octreotide
Spironolactone
Lactulose
57. Which medication can cause myelosuppression, hepatotoxicity and pulmonary toxicity, and is used in IBD?
Mesalazine
Methotrexate
Vedoluzimab
Budesonide
58. Which of the following is true about "Prescription Only Medicine"?
Is unscheduled medication
Can be sold without supervision
Requires a prescription for supply
Available over the counter
59. What kind of drug is Famotidine?
Laxative
H2 receptor antagonist
PPI
Antacid
60. Which class of diabetes medications can cause pancreatitis?
DPP-4 inhibitors
SGLT2 inhibitors
Sulfonylureas
GLP-1 agonists
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