Pharm Revision

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Willow22
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Last updated: October 29, 2024
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First submittedOctober 29, 2024
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1. What is the mechanism of action for Disulfiram?
Blocks opioid receptors
Inhibits aldehyde dehydrogenase
Reduces cravings
Enhances excitatory neurotransmitters
2. What is the main concern with drugs in Category D?
Potential for foetal damage
Evidence of reversible effects
Inadequate information on human risks
Lack of studies in animals
3. What is the mechanism of action of Dexamethasone?
Block NK1 receptors
Inhibit H2 receptors
Stimulate appetite
Inhibit prostaglandin synthesis
4. Which diuretic is known to cause hyperkalemia?
Furosemide
Indapamide
Amiloride
Hydrochlorothiazide
5. What type of drug is Hyoscine Hydrobromide?
H2 receptor antagonist
5HT-3 antagonist
Antimuscarinic
D2 receptor antagonist
6. What does "down-scheduling" refer to?
Adding a drug to the controlled substance list
Reducing the classification level of a drug
Increasing restrictions on a drug
Banning a drug entirely
7. What is a side effect of Thiazide diuretics?
Hypokalemia
Oedema
Hypoglycemia
Hypertension
8. What is the primary action of Metoclopramide?
Block H1 receptors
Reduce fluid retention
Increase gastrointestinal motility
Inhibit serotonin receptors
9. What is the main side effect of corticosteroids like Prednisolone in IBD treatment?
Weight loss
Constipation
Nausea
Fluid retention
10. Which insulin type is considered "long-acting"?
Isophane
Neutral
Asparat
Glargine
11. What is the primary action of SGLT2 inhibitors?
Decrease hepatic glucose production
Stimulate insulin secretion
Increase glucose uptake
Inhibit renal glucose reabsorption
12. What is the purpose of drug scheduling?
To enhance marketing strategies
To classify medicines for regulatory control
To evaluate therapeutic effects
To categorise drugs by efficacy
13. Which drug is commonly used for ascites management?
Lactulose
Dexamethasone
Propranolol
Spironolactone
14. What is the main action of 5HT-3 antagonists like Dolasetron?
Inhibit serotonin action in the CTZ
Increase gastrointestinal motility
Enhance appetite
Block dopamine receptors
15. What adverse effect is associated with SGLT2 inhibitors?
Hypoglycemia
Polyuria
Constipation
Weight gain
16. What is the main mechanism of action of H2 receptor antagonists?
Neutralize gastric acid
Block histamine on parietal cells
Inhibit proton pumps
Block dopamine receptors
17. Which medication is a D2 receptor antagonist?
Domperidone
Fosaprepitant
Ondansetron
Hyoscine
18. What does Category B1 imply about a drug?
No evidence of foetal damage in animal studies
Insufficient human studies
Harmful effects shown in animals
Proven teratogenic effects in humans
19. What effect does metformin primarily have on the liver?
Decrease glucose production
Increase insulin sensitivity
Increase glucose production
Decrease lipolysis
20. What is a significant limitation of animal studies in assessing drug safety for humans?
They provide clear human context
They are more reliable than human studies
They always show direct human risks
They are often inconclusive
21. What is the primary role of antimuscarinics in nausea treatment?
Block serotonin
Enhance dopamine effects
Block acetylcholine
Increase motility
22. What is a potential side effect of stimulant laxatives?
Intestinal obstruction
Fluid retention
Abdominal cramps
Nausea
23. Which laxative should not be used in children?
Stool-softening laxatives
Saline laxatives
Stimulant laxatives
Bulk-forming laxatives
24. What is the mechanism of action of Furosemide?
Inhibit sodium/chloride co-transporter
Inhibit Na+/K+/2A-� symporter
Block aldosterone
Retain fluid osmotically
25. Which pregnancy category should never be used during pregnancy?
Category B
Category D
Category A
Category X
26. Which of the following is a PPI?
Docusate
Famotidine
Omeprazole
Calcium Carbonate
27. Which drug is an example of a bulk-forming laxative?
Ispaghula
Bisacodyl
Lactulose
Docusate
28. Which drug is an NK1 antagonist?
Dexamethasone
Metoclopramide
Hyoscine
Aprepitant
29. What is the action of bulk-forming laxatives like psyllium?
Absorb water and stimulate peristalsis
Retain fluid osmotically
Irritate intestinal mucosa
Soften the stool
30. Which type of insulin is classified as short-acting?
Glargine
Asparate
Isophane
Neutral
31. When prescribing medication during pregnancy, which practice point is crucial?
Use only new drugs
Prescribe without concern for fetal risk
Only prescribe if benefits outweigh risks
Recommend any drug with known safety
32. Which of the following categories is NOT a pregnancy category?
A
C
D
S
33. What is a common adverse effect of antacids containing magnesium?
Constipation
Nausea
Abdominal pain
Diarrhea
34. Which laxative should be avoided in patients with intestinal obstruction?
Lactulose
Psyllium
Glycerol
Docusate
35. What is a common systemic condition caused by corticosteroids used in IBD treatment?
Hypertension
Cushing's syndrome
Increased appetite
Infertility
36. Which laxative works by irritating the intestinal mucosa?
Glycerol
Bisacodyl
Docusate
Psyllium
37. Which medication is typically used for the PREVENTION of varices?
Terlipressin
Propranolol
Acamprosate
Naltrexone
38. What limitation is associated with the alphabetical hierarchy of pregnancy categories?
It considers drug dosage
It implies a direct correlation with human risk
It accurately reflects risk levels
It ignores clinical context
39. What is the mechanism of action of sulfonylureas?
Decrease hepatic glucose production
Inhibit glucose reabsorption
Increase insulin release from beta cells
Slow gastric emptying
40. What class does loperamide belong to?
Stimulant laxatives
Osmotic laxatives
Antimuscarinics
Antidiarrhoeals
41. Which drug is a TNF-a antagonist?
Mesalazine
Azathioprine
Budesonide
Infliximab
42. What is the primary action of Metformin?
Block DPP-4 enzymes
Increase glucose uptake and decrease hepatic production
Increase insulin secretion
Inhibit glucose reabsorption
43. Which pregnancy category indicates that a drug has been taken by a large number of pregnant women without an increase in malformations?
Category A
Category C
Category B
Category X
44. What side effect is associated with corticosteroids like Dexamethasone?
Fluid retention
Nausea
Increased motility
Constipation
45. What is the primary function of glucocorticoids in IBD treatment?
Increase inflammation
Inhibit inflammatory mediators
Block TNF-a
Promote healing
46. What should Naltrexone not be used in combination with?
Liver impairment
Acamprosate
Disulfiram
Alcohol
47. What is the effect of potassium-sparing diuretics?
Cause fluid retention
Cause sodium loss without potassium loss
Increase potassium loss
Reduce sodium loss
48. What defines a "Pharmacy Medicine"?
Safe to use but may need pharmacist advice
Available only in hospitals
Requires medical supervision
Requires a prescription
49. Triple therapy for H. pylori treatment typically includes which components?
H2 blocker + Metronidazole and Amoxicillin
Lactulose + Clarithromycin + PPI/Antacid
Antacid + PPI + Amoxicillin
PPI + 2x Amoxicillin, Clarithromycin, or Metronidazole
50. What is a potential adverse effect of using Azathioprine?
Increased inflammation
Thrombocytopenia
Weight gain
Hypertension
51. Which class of drugs does Ondansetron belong to?
5HT-3 antagonists
Corticosteroids
Antimuscarinics
D2 receptor antagonists
52. Which class of drugs includes Semaglutide?
GLP-1 agonists
Sulfonylureas
DPP-4 inhibitors
SGLT2 inhibitors
53. Which drug is often prescribed to manage ascites?
Acamprosate
Propranolol
Spironolactone
Furosemide
54. What is the primary role of antihistamines in treating nausea?
Block H1 receptors in the VC
Enhance gastric motility
Block serotonin receptors in the VC
Block acetylcholine in the VC
55. What is the primary action of 5-ASA drugs?
Antimicrobial effects
Analgesic effects
Anti-inflammatory effects
Immunosuppressive effects
56. Which medication is used for variceal TREATMENT?
Propranolol
Terlipressin with Octreotide
Lactulose
Spironolactone
57. Which medication can cause myelosuppression, hepatotoxicity and pulmonary toxicity, and is used in IBD?
Budesonide
Methotrexate
Mesalazine
Vedoluzimab
58. Which of the following is true about "Prescription Only Medicine"?
Can be sold without supervision
Is unscheduled medication
Requires a prescription for supply
Available over the counter
59. What kind of drug is Famotidine?
Laxative
H2 receptor antagonist
Antacid
PPI
60. Which class of diabetes medications can cause pancreatitis?
GLP-1 agonists
SGLT2 inhibitors
Sulfonylureas
DPP-4 inhibitors
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