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Hints
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Answer
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Master of disguises and Spiderman's first villain
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Chameleon
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Engineer who had spinal cancer and created wings that made him fly
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Vulture
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Doctor who had a set of mechanical limbs fused to his body
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Doctor Octopus
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Made of sand
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Sandman
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Lost an arm and found a cure that turned him into a reptile
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Lizard
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Struck by lightning after working on a power line and became a living electric capacitor
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Electro
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Uses tech to create illusions
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Mysterio
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CEO of Oscorp with a personal vendetta against Spiderman
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Green Goblin
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Spiderman's best friend
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New Goblin
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Obsessed with finding an 'equal'
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Kraven
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Criminal who underwent a test that gave him superhuman strength, funded by J. Jonah Jameson to defeat Spiderman but went rogue
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Scorpion
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Man trapped in an armoured suit
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Rhino
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Uses shockwaves to rob banks
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Shocker
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The Kingpin of crime
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Kingpin
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The living vampire
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Morbius
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Professor who clones people and likes to torment Spiderman with them
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Jackal
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Master burglar is a love interest and part time ally of Spiderman, also fighting him at times
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Black Cat
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Discovered secret OSCORP lair and tweaked a formula that gave him the abilities of Spiderman's arch nemesis without the insanity
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Hobgoblin
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"We are ^"
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Venom
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The technical offspring of the above
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Carnage
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Engineer who creates evil gadgets to cause crimes
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Tinkerer
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A living robot which is designed to solve any problem
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Living Brain
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A notorious crime lord in NYC
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Big Man
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Created a suit that is perfectly capable of killing Spiderman
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Spider Slayer
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A professional criminal who has the alias of different people
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Crime Master
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A scientist who was covered in a liquid metallic alloy that gave him super strength and allowed him to generate heat and radiation
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Molten Man
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A poor scientist who gains powers from meteor gas
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Looter
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A former college teacher and partner of Norman Osborn that became a cyborg after being betrayed by him
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Robot Master
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No description
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Finisher
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A Maggia lieutenant to Silver Mane with super strength
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Man Mountain Marko
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An aging crime boss that is later turned into a cyborg with super strength
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Silvermane
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Teenage prodigy that created technology allowing him to equip clawed gauntlets, operating as a petty thief
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Prowler
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A name given to two kangaroo-themed villains
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Kangaroo
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The son of Wilson Fisk
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Schemer
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An alien found by the hunter that quickly grew gigantic in size and possesses superhuman strength and bracelets that allow interdimensional teleportation
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Gog
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A lesser like criminal with gibbon-like abilities
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Gibbon
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A mobster who has most of his skull replaced with an unbendable steel alloy
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Hammerhead
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Was transformed into a werewolf after being exposed to the alien godstone
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Man-Wolf
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A name given to different tarantula-themed villains
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Tarantula
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A superhuman with telepathic powers
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Mindworm
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An ex-professional wrestler who wears a grizzly bear-themed outfit
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Grizzly
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A criminal who was imprinted with the genetic code of a housefly
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Human Fly
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A former Roxxon employee who can manipulate his molecules
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Will o' the Wisp
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Rides a BIG WHEEL
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Big Wheel
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An accomplice of the hunter who uses voodoo potions and magic
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Calypso
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A former crewman who gained aquakinetic abilities after an accident in the fight between Spiderman and Namor
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Hydro-Man
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The alias of a gentleman-like crime lord with the alias used by different people most notably Wilson Fisk's son
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Rose
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A Native American who was bred to be a perfect warrior prophesied to stop a future threat that might destroy the world, gaining the ability to transform into a mountain lion werecat at will
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Puma
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A chemist whose suit allows him to move at nearly 30 miles per hour (48 km/h). He is almost impossible to grasp and he is incredibly maneuverable
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Slyde
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A mad scientist who has a disintegrating touch and a homeless man who has two-large weapons on his shoulders and was later mutated into a golem-like creature
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Styx and Stone
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A highly skilled and ruthless assassin who came under the employ of the gentlemanly crime lord during one of the many crime-gang wars and became his confidante as well as his chief enforcer.
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Delilah
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A tarantula-themed martial artist
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Black Tarantula
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A member of the Inheritors who can drain the life force of Spider-Totems
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Morlun
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An insectoid creature from the Astral Plane
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Shathra
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A gray-resembling Goblin whose alias was used by different people
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Gray Goblin
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Channels negative energy and wields a sword
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Mister Negative
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Criminal who can convert any vehicle into a highly powered one
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Overdrive
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A drug addict turned into a superpowered being able to adapt to injuries by metamorphing into new forms.
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Freak
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The worlds first "live-streaming super-villain"
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Screwball
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A brain-damaged criminal who lacks emotions
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Massacre
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A panda-themed supervillain
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Panda-Mania
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The CEO of Empire Unlimited whose suit enables him to copy the powers of anyone imprisoned in his statis tubes
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Regent
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A human-turned-demon
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Kindred
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Physics professor and vice-chancellor of Empire State University who became a criminal mastermind as a way to prevent budget cuts for higher education. He created a unique special power armour suit which utilised "gravity-pump circuitry" to allow him to manipulate photons for a variety of effects
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Lightmaster
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Originally a clone of Miles Warren, he can levitate, kill by touch, control his density and telepathy.
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Carrion
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A human-sized semi-humanoid reptile with superhuman strength, hypnotic powers, and the ability to mentally control other reptiles, created in an accident by Curt Conners when it was tested on
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Iguana
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A criminal genius and a former member of Fisk's criminal organisation. He is a former hitman in the Las Vegas division of Hydra and was empowered by the laboratory machine's of Farley Stillwell's brother Harlan Stillwell, becoming "The ^"
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Answer
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Scientist turned criminal who can create portals leading to other dimensions
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Spot
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A master mercenary and assassin
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Foreigner
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Multiple abilities ranging from artificially heightened physicality, to super energy manipulation and self-healing. Is a recurring villain of Ghost Rider
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Sin-Eater
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Two brothers who became werewolves and Drug Cartel members who expanded into Texas
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Lobo Brothers
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Introduced as a red herring to suggest the possibility of a third individual that was the original Peter Parker during the "Maximum Collage" story arc, he is one of the clones created by Dr. Miles Warren, to be his enforcer and protector. However, he is actually a clone of Ben Reilly, who is himself a clone of Spiderman.
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Spidercide
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A scientist who became a humanoid dinosaur using the same method that Curt Connors used to turn him into a reptile
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Stegron
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A witch-hunter of Salem, Massachusetts in the 17th century who had been given mystical power by the Dark Rider
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Witch-Slayer
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A rabbit-themed supervillain, who pilots a giant rabbit mech and has a large arsenal of weapons at her disposal
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White Rabbit
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A former monk of Dakoth-Kuru, a sect that had managed to use their teachings to unlock the full potential of their minds, giving them incredible mental powers. The monk had more powers, including the ability to control the twelve others and took control of the entire brotherhood
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Black Abbot
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Following an experiment by Project Pegasus, he gained the ability to draw electrical energy into one's body
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Incandescent Man
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An albino mob enforcer with very hard skin
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Tombstone
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A sound-manipulating supervillain
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Shriek
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An expert martial artist and swordsman who wields cryonic swords that can freeze anyone in their place
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Coldheart
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Criminal who uses tech and flying wings to cause chaos
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Beetle
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A former baseball player who uses boomerangs as weapons
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Boomerang
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A demon who manipulates Spiderman and other superheroes into making deals with him
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Mephisto
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A supervillain who wields ring-based weapons
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Ringer
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A former Nazi and beekeeper whose skeleton is surrounded by a swarm of bees
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Swarm
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A halloween themed mercenary/villain whose alias was used by different people
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Jack O'Lantern
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A chemist with super-speed and former member of the Squadron Sinister
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Speed Demon
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A geneticist who was turned into a humanoid rat by Arnim Zola
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Vermin
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A nearly-mindless duplicate of Spiderman
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Doppelganger
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A supervillain who is able to absorb and store electricity
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Supercharger
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Norman Osborn tests the incomplete version of the formula on an Oscorp employee, driving him insane and causing him to transform into a demonic being with super strength and agility, claws, talons, fangs, glowing green eyes, and near-impenetrable skin that is capable of withstanding several close range bullet shots
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Proto-Goblin
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A hippopotamus who was uplifted by the High Evolutionary and gained an anthropomorphic form
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Hippo
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The leader of the Enforcers
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Montana
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The strongest member of The Enforcers
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Ox
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Member of The Enforcers
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Fancy Dan
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The man who killed Spiderman's uncle
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Burglar
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Spiderman's bully
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Flash Thompson
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The editor in chief of The Daily Bugle
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J. Jonah Jameson
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