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Hint
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Answer
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Deposition of immune complexes, formed in conjunction with beta-hemolytic group A Streptococcus infection, on the glomerular membranes
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Acute Poststreptococcal Glomerulonephritis
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Deposition of immune complexes from systemic immune disorders on the glomerular membrane
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Rapidly Progressive Glomerulonephritis
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Attachment of a cytotoxic antibody formed during viral respiratory infections to glomerular and alveolar basement membranes
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Goodpasture syndrome
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Antineutrophilic cytoplasmic autoantibody (ANCA) binds to neutrophils in vascular walls, producing damage to small vessels in the lungs and glomerulus
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Wegener’s granulomatosis
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Occurs primarily in children after viral respiratory infections; a decrease in platelets disrupts vascular integrity
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Henoch-Schonlein Purpura
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Thickening of the glomerular membrane after IgG immune complex deposition associated with systemic disorders
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Membranous Glomerulonephritis
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Cellular proliferation affecting the capillary walls or the glomerular basement membrane, possibly immune mediated
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Membranoproliferative Glomerulonephritis
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Deposition of IgA on the glomerular membrane resulting from increased levels of serum IgA
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IgA Nephropathy
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Marked decrease in renal function resulting from glomerular damage precipitated by other renal disorders
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Chronic Glomerulonephritis
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Disruption of the podocytes occurring primarily in children after allergic reactions and immunizations; dysfunction of T-cell immunity
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Minimal change disease
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Disruption of podocytes in certain areas of glomeruli associated with heroin and analgesic abuse and with HIV and hepatitis viruses
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Focal segmental glomerulosclerosis
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Genetic disorder showing lamellated and thinning glomerular basement membrane
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Alport syndrome
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Most common cause of End Stage Renal Disease
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Diabetic Nephropathy
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Damage to the glomerular membrane occurs as a result of glomerular membrane thickening and increased deposition of cellular and noncellular material within the glomerular matrix.
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Diabetic Nephropathy
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Damage to renal tubular cells caused by ischemia or toxic agents
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Acute tubular necrosis
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Inherited in association with cystinosis and Hartnup disease or acquired through exposure to toxic agents
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Fanconi syndrome
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Inherited defect in the production of normal uromodulin by the renal tubules and increased uric acid causing gout
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Uromodulin-associated kidney disease
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Inherited defect of tubular response to ADH or acquired from medications
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Nephrogenic diabetes insipidus (DI)
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Inherited autosomal recessive trait
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Renal glucosuria
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Infection of the renal tubules and interstitium related to interference of urine flow to the bladder, reflux of urine from the bladder, and untreated cystitis
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Acute pyelonephritis
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Recurrent infection of the renal tubules and interstitium caused by structural abnormalities affecting the flow of urine
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Chronic pyelonephritis
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Allergic inflammation of the renal interstitium in response to certain medications
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Acute interstitial nephritis
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Ascending bacterial infection of the bladder
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Cystitis
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enzyme deficient in phenylketonuria
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Phenylalanine hydroxylase
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FeCl3 tube test color in PKU
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blue-green
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Confirmatory test for PKU
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Ion exchange HPLC
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Enzyme deficient in Type 1 Tyrosinemia/Tyrosyluria
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Fumarylacetoacetate hydrolase
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Enzyme deficient in Type 2 Tyrosinemia/Tyrosyluria
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Tyrosine aminotransferase
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Enzyme deficient in Type 3 Tyrosyluria/Tyrosinemia
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p-hydroxyphenylpyruvic acid dioxygenase
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Unique screening test for Tyrosyluria/Tyrosinemia
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Nitroso-naphthol
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Color of the unique screening test for Tyrosyluria/Tyrosinemia
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orange-red
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FeCl3 tube test color in Tyrosyluria/Tyrosinemia
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transient green
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Enzyme deficient in Alkaptonuria
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Homogentisic acid oxidase
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FeCl3 tube test color in Alkaptonuria
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Transient blue
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Substance secreted by the tumor in melanuria that oxidizes melanogen to melanin
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5,6-dihydroxyindole
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FeCl3 tube test color in Melanuria
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Gray/Black precipitate
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1st Unique screening test for Melanuria
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Sodium nitroprusside test
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2nd Unique screening test for Melanuria
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Ehrlich Test
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Color of the unique screening test for Melanuria
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Red
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Enzyme deficient in MSUD
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BCKD
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Unique screening test for MSUD
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2,4-DNPH
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Mnemonic for the acidemias involved in Organic Acidemias
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IPM
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Unique screening test for Methymalonic acidemia
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p-nitroaniline tes
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Color of the unique screening test for Methylmalonic acidemia
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Emerald green
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Unique screening test for Indicanuria
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Obermayer’s test
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Color of the unique screening test for Indicanuria
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Violet
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FeCl3 tube test color in Argentaffinoma
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Blue-green
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Unique screening test for Argentaffinoma
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Nitrosonaphthol with nitrous acid
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Color of the unique screening test for Argentaffinoma
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Violet
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Mnemonic for the amino acids involved in the defective tubular reabsorption in Cystinuria
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COLA
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Unique screening test for Cystinuria
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Brand’s Modification of Legal’s nitroprusside
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Reagent of the unique screening test for Cystinuria
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Cyanide nitroprusside
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Color of the unique screening test for Cystinuria
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Red-purple
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Not metabolized in Homocystinuria
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Methionine
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Enzyme deficient in Homocystinuria
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Cystathione B-synthase
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Unique screening test for Homocystinuria
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Silver-nitroprusside test
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Color of the unique screening test for Homocystinuria
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Red-purple
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Enzyme deficient in Lesch-Nyhan Disease
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hypoxanthine guanine phosphoribosyltransferase
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